Results 221 to 230 of about 12,037,247 (302)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Development of a Novel Low-Cost Knee Brace to Quantify Human Knee Function During Dynamic Tasks: A Feasibility Study from the North-West Province. [PDF]

Sensors (Basel)
Thomson I, Kramer M.
europepmc   +1 more source

Hybrid closed-loop insulin delivery improves glycaemic control compared with sensor-augmented pump therapy: A meta-analysis of 'free-living' randomised trials in type 1 diabetes. [PDF]

Diabet Med
Sidki AS, Highton PJ, O'Mahoney LL, Wilkinson TJ.   +3 more
europepmc   +1 more source

Compact Optical Visual Magnification System with a Wide Field of View. [PDF]

Sensors (Basel)
Milman U, Kaufmann J, Arieli Y.
europepmc   +1 more source

Prospective Diagnostic Accuracy and Technical Feasibility of Artificial Intelligence-Assisted Rib Fracture Detection on Chest Radiographs: Observational Study.

JMIR Med Inform
Huang ST, Liu LR, Tsai MF, Huang MY, Chiu HW.   +4 more
europepmc   +1 more source

Building multiscale Markov state models by systematic mapping of temporal communities. [PDF]

Bioinformatics
Nitskansky N, Clein K, Raveh B.
europepmc   +1 more source