Results 51 to 60 of about 649 (214)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Profiles of the unitarity triangle and CP-violating phases in the standard model and supersymmetric theories [PDF]

The European Physical Journal C, 1999
We report on a comparative study of the profile of the CKM unitarity triangle, and the resulting CP asymmetries in B decays, in the standard model and in several variants of the minimal supersymmetric standard model (MSSM), characterized by a single phase in the quark flavour mixing matrix. The supersymmetric contributions to the mass differences ΔM_d,
Ali, Ahmed, London, David
openaire   +3 more sources

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Blunt Dissection: A Solution to Prevent Bile Duct Injury in Laparoscopic Cholecystectomy

Chinese Medical Journal, 2015
Background: Laparoscopic cholecystectomy (LC) has been a standard operation and replaced the open cholecystectomy (OC) rapidly because the technique resulted in less pain, smaller incision, and faster recovery.
Xiu-Jun Cai, Han-Ning Ying, Hong Yu, Xiao Liang, Yi-Fan Wang, Wen-Bin Jiang, Jian-Bo Li, Lin Ji   +7 more
doaj   +1 more source

CP-violation and unitarity triangle test of the Standard Model [PDF]

Physics of Particles and Nuclei, 2008
Phenomenological issues of the CP violation in the quark sector of the Standard Model are discussed. We consider quark mixing in the SM, standard and Wolfenstein parametrization of the $CKM$ mixing matrix and unitarity triangle. We discuss the phenomenology of the CP violation in $K^{0}_{L}$ and $B_{d}^{0} (\bar B_{d}^{0})$-decays.
openaire   +2 more sources

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin, Sofia Waldorf, Janina von der Gablentz, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Sarah Bernsen   +8 more
wiley   +1 more source

Plant Species Recognition Using Triangle-Distance Representation

IEEE Access, 2019
Plant species recognition using leaf images is a highly important and challenging issue in botany and pattern recognition. A center problem of this task is how to accurately extract leaf image characteristics and quickly calculate the similarity between ...
Chengzhuan Yang, Hui Wei
doaj   +1 more source

Unitarity Triangle Analysis in the Standard Model and Sensitivity to New Physics

, 2003
Invited talk at the Workshop on the CKM Unitarity Triangle, IPPP Durham, April 2003 (eConf C0304052). 9 pages LaTeX, 15 eps figures.
Ciuchini M, Franco E, LUBICZ, Vittorio, Parodi F, Silvestrini L, Stocchi A.   +5 more
openaire   +3 more sources

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source