Results 51 to 60 of about 1,205,046 (341)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Comparative transcriptome analysis of maize (Zea mays L.) seedlings in response to copper stress

open access: yesOpen Life Sciences
Copper (Cu) is considered one of the major heavy metal pollutants in agriculture, leading to reductions in crop yield. To reveal the molecular mechanisms of resistance to copper stress in maize (Zea mays L.) seedlings, transcriptome analysis was ...
Zhang Mengyan   +4 more
doaj   +1 more source

The ambient air quality standards, green innovation, and urban air quality: evidence from China

open access: yesScientific Reports, 2023
As China’s economy transitions, environmental issues have become a major concern. This study examines the impact of Ambient Air Quality Standards (AAQS) on urban air quality using panel data from 284 cities in China from 2006 to 2019.
Han Zhang   +3 more
doaj   +1 more source

Review on Quality Safety Standards and Critical Control Points of Chondroitin Sulfate Sodium

open access: yesShipin gongye ke-ji, 2022
Chondroitin sulfate sodium is an acidic mucopolysaccharide extracted from animal cartilage, and has been widely used in the world as anti-osteoarthritis and health food. It is difficult to control the quality and safety of chondroitin sulfate sodium, due
Lin ZHAO   +7 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Construction of a quantitative model for ski resort water demand and preliminary exploration of drainage irrigation pathways

open access: yesScientific Reports
In China, natural snowfall is insufficient, and ski resorts often require artificial snowmaking in winter and turf management in summer, which results in high overall water consumption and considered as one of the high water-consuming service industries,
Jialin Liu   +4 more
doaj   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Carbon emission characteristics and carbon reduction analysis of employee travel-taking a research institute as an example

open access: yesEnergy Informatics
This paper adopts the “baseline scenario method” to construct a comprehensive model for calculating and reducing carbon emissions generated by employee travel, including the accounting of carbon emissions from commuting and business travel, as well as ...
Lan Zhang   +4 more
doaj   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

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