Results 71 to 80 of about 1,205,046 (341)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

User behavior and energy-saving potential of electric washing machines

open access: yesEnergy Informatics
With the intensification of the global energy crisis and the increase in environmental awareness, energy-saving problems related to household appliances have garnered widespread attention.
Lu Qiao   +4 more
doaj   +1 more source

Research on the Positioning of Precision Nutrition Foods and the Current Status of Relevant Regulations and Standards

open access: yesShipin gongye ke-ji, 2022
As a new concept, ''Precision Nutrition'' has no unified definition at present. In this paper, ''Precision Nutrition'' refers to ''the field of formulating dynamic nutritional recommendations, products or services based on the characteristics of ...
Xi WU   +6 more
doaj   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Analysis of user behavior and energy-saving potential of electric water heaters

open access: yesEnergy Informatics
As global energy resources get more limited and environmental problems worsen, it is crucial to enhance energy efficiency and reduce energy consumption in end-use products.
Jialin Liu   +4 more
doaj   +1 more source

Intelligent Content-Centric Networking Routing Strategy: A Bacterial Quorum Inspired Pattern

open access: yesComplexity, 2021
In recent years, the Content-Centric Networking (CCN) has attracted much attention from the global Internet experts; in particular, it has demonstrated the outstanding effect on the application in the field of Internet of Things (IoT).
Hong Yang   +3 more
doaj   +1 more source

Consideration of building a common platform of collaborative learning environment [PDF]

open access: yes, 2001
This paper reports on considerations about a common and basic functions/components for building a collaborative learning environment. We make efforts to specify the technological issues towards the future standardization of this environment through our ...
Cristea, Alexandra I.   +2 more
core  

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

The gold standard: not a golden standard [PDF]

open access: yesBMJ, 2005
Studies that evaluate a new diagnostic test, procedure, or method should do so by comparing it with a time honoured alternative that is considered to be the current standard in the field. In this context the meaning of the word standard is “authoritative or recognised exemplar of quality or correctness.” “Gold standard” is the popular term to describe ...
openaire   +4 more sources

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

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