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How High Can the Standardized Uptake Value Be?
Clinical Nuclear Medicine, 2002Positron emission tomography using the glucose analog fluorine-18 fluorodeoxyglucose (FDG PET) provides a unique means for the in vivo noninvasive assessment of metabolism in tumors and other disorders. A high degree of increased metabolism in a lesion is often suggestive of malignancy in the appropriate clinical setting, whereas low levels of FDG ...
Hongming Zhuang +3 more
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Image reconstruction, quantification and standard uptake value [PDF]
, 2000 One of the important characteristics of positron emission tomography (PET) is the ability to quantify metabolic function in vivo. To achieve this goal, radioactivity data (activity per volume) measured by PET is transformed into metabolic parameters of interest by using the simultaneously measured radioactivity in blood and an appropriate physiological
H. Herzog, Richard D. Hichwa
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A threshold method to improve standardized uptake value reproducibility
Nuclear Medicine Communications, 2000Although standardized uptake values (SUV) are widely used to quantify the uptake of 18F-fluorodeoxyglucose (18F-FDG) in tumours, there are systematic differences in the way this index is applied by different investigators. The aims of this study were to compare the effects of using maximum or mean region counts in the calculation of SUV and to ...
J. R. Lee +3 more
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Automated 11C-PiB Standardized Uptake Value Ratio
Academic Radiology, 2008Radiotracers such as (11)C-PiB have enabled the in vivo imaging of amyloid-beta plaques in the brain, one of the histopathologic hallmarks of Alzheimer's disease (AD). Standardized uptake value ratio (SUVR) has become the most common normalization for (11)C-PiB as it does not require dynamic scans or blood sampling.
Victor L. Villemagne +11 more
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Standardized Uptake Value Ratio-Independent Evaluation of Brain Amyloidosis
Journal of Alzheimer's Disease, 2016The assessment of in vivo18F images targeting amyloid deposition is currently carried on by visual rating with an optional quantification based on standardized uptake value ratio (SUVr) measurements. We target the difficulties of image reading and possible shortcomings of the SUVr methods by validating a new semi-quantitative approach named ELBA.
Chincarini, Andrea +8 more
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Annals of Nuclear Medicine, 2013
The objective of this study is to determine the range of SUVmax of 68Ga-DOTATATE in normal organs and tumoral lesions and establish uptake unrelated to NET.One hundred and twenty patients (57 men, 63 women), who underwent (68)Ga-DOTATATE PET/CT imaging in our institution were analyzed.
Seher Ünal +6 more
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The objective of this study is to determine the range of SUVmax of 68Ga-DOTATATE in normal organs and tumoral lesions and establish uptake unrelated to NET.One hundred and twenty patients (57 men, 63 women), who underwent (68)Ga-DOTATATE PET/CT imaging in our institution were analyzed.
Seher Ünal +6 more
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Alzheimer's & Dementia, 2018
AbstractIntroductionKlunk et al. recently proposed a means of standardizing quantitation of amyloid burden from positron emission tomography scans to a common Centiloid scale, and we have applied that method to florbetapir.MethodsFlorbetapir and Pittsburgh compound B scans were acquired for 46 mixed clinical presentation subjects within 18 ± 20 days ...
Mark A. Mintun +8 more
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AbstractIntroductionKlunk et al. recently proposed a means of standardizing quantitation of amyloid burden from positron emission tomography scans to a common Centiloid scale, and we have applied that method to florbetapir.MethodsFlorbetapir and Pittsburgh compound B scans were acquired for 46 mixed clinical presentation subjects within 18 ± 20 days ...
Mark A. Mintun +8 more
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Nuclear Medicine Communications, 2004
Among clinicians who use positron emission tomography (PET), the standardized uptake value (SUV) is a popular semi-quantitative value that can be easily assessed whenever a PET study is performed under physiological and pathological conditions. It provides an index of regional tracer uptake normalized to the administered dose of tracer.
Lucignani, G. +2 more
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Among clinicians who use positron emission tomography (PET), the standardized uptake value (SUV) is a popular semi-quantitative value that can be easily assessed whenever a PET study is performed under physiological and pathological conditions. It provides an index of regional tracer uptake normalized to the administered dose of tracer.
Lucignani, G. +2 more
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Evaluation of Standardized Uptake Value to Assess Cerebral Glucose Metabolism
Clinical Nuclear Medicine, 2000When the cerebral metabolic rate of glucose (CMRglc) is to be measured, arterial blood sampling is usually required for fluorine-18 fluorodeoxyglucose (FDG) and positron emission tomography (PET) studies. However, blood sampling is inconvenient because it requires several staff members and is invasive for patients.To assess cerebral glucose metabolism ...
Hajime Kitagaki +6 more
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European Journal of Nuclear Medicine, 1996
While the evident advantages of absolute metabolic rate determinations cannot be equalled by static image analysis of fluorine-18 fluorodeoxyglucose positron emission tomographic (FDG PET) studies, various algorithms for the normalization of static FDG uptake values have been proposed.
C Reichel +6 more
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While the evident advantages of absolute metabolic rate determinations cannot be equalled by static image analysis of fluorine-18 fluorodeoxyglucose positron emission tomographic (FDG PET) studies, various algorithms for the normalization of static FDG uptake values have been proposed.
C Reichel +6 more
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