Results 71 to 80 of about 118,834 (253)

The accuracy of positron emission tomography in the detection of posttransplant lymphoproliferative disorder

Haematologica, 2013
We investigated sensitivity, specificity, positive predictive value, negative predictive value and accuracy of 18F-fluorodeoxyglucose-positron emission tomography in 170 cases with suspected or biopsy-proven posttransplant lymphoproliferative disorder ...
Daan Dierickx, Thomas Tousseyn, Annelies Requilé, Raf Verscuren, Xavier Sagaert, Julie Morscio, Iwona Wlodarska, An Herreman, Dirk Kuypers, Johan Van Cleemput, Frederik Nevens, Lieven Dupont, Anne Uyttebroeck, Jacques Pirenne, Christiane De Wolf-Peeters, Gregor Verhoef, Lieselot Brepoels, Olivier Gheysens   +17 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Quantitative evaluation of 67Ga-citrate scintigraphy in the management of nephritis

Scientific Reports
In 67Ga-citrate scintigraphy (Ga-S), visual assessment is used by evaluating renal-uptake comparison with liver and spine and is simple and objective. We adopted the standardized uptake value (SUV) for 67Ga-citrate and proposed two quantitative indices ...
Noritake Matsuda, Hideki Otsuka, Ryosuke Kasai, Tamaki Otani, Leah Anne Christine Locsin Bollos, Shota Azane, Yamato Kunikane, Yoichi Otomi, Yuya Ueki, Mana Okabe, Masafumi Amano, Masanori Tamaki, Shu Wakino, Shoichiro Takao, Masafumi Harada   +14 more
doaj   +1 more source

A new method in thoracoscopic inferior mediastinal lymph node biopsy: a case report

Journal of Medical Case Reports, 2009
Introduction We performed video-thoracoscopy with a video-mediastinoscope to conduct a mediastinal lymph node biopsy. Here, we discuss the various advantages of the method.
Sanlı Maruf, Isik Ahmet F, Tuncozgur Bulent, Elbeyli Levent   +3 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Alteration of brain metabolism in lacunar stroke based on 18F-FDG-PET/MRI analysis

Frontiers in Neurology
Background and PurposeLacunar stroke (LS) is caused by occlusion of the penetrating branches of the major cerebral arteries and includes small and deep infarcts. Our study aimed to explore brain metabolic alterations in LS.MethodsSeventy individuals with
Rong-Rong Huang, Rong-Rong Huang, Mou-Xiong Zheng, Mou-Xiong Zheng, Jia-Jia Wu, Jia-Jia Wu, Yun-Ting Xiang, Yun-Ting Xiang, Ling-Ling Li, Ling-Ling Li, Jing Jin, Jing Jin, Jian-Hui He, Jian-Hui He, Xin Gao, Jie Ma, Jie Ma, Xu-Yun Hua, Xu-Yun Hua, Jian-Guang Xu, Jian-Guang Xu, Jian-Guang Xu   +21 more
doaj   +1 more source

Prognostic Value of Lymph Node-To-Primary Tumor Standardized Uptake Value Ratio in Esophageal Squamous Cell Carcinoma Treated with Definitive Chemoradiotherapy [PDF]

, 2020
Chia-Hsin Lin, Tsung‐Min Hung, Yu-Chuan Chang, Chia‐Hsun Hsieh, Ming‐Chieh Shih, Shih-Ming Huang, Chan‐Keng Yang, Ching‐Fu Chang, Sheng-Chieh Chan, Wing‐Keen Yap   +9 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source