Results 71 to 80 of about 239,832 (344)

Standardized uptake values in FDG PET/CT for prosthetic heart valve endocarditis: a call for standardization [PDF]

Journal of Nuclear Cardiology, 2018
The significance of and threshold values for the standardized uptake value (SUV) in FDG PET/CT to diagnose prosthetic heart valve (PHV) endocarditis (PVE) are unclear at present.A literature search was performed in the PubMed and EMBASE medical databases, comprising the following terms: (FDG OR *fluorode* OR *fluoro-de*) AND (endocarditis OR prosthetic
Scholtens, Asbjørn M., Swart, Laurens E, Kolste, Henryk J Te, Budde, Ricardo P J, Lam, Marnix G E H, Verberne, Hein J   +5 more
openaire   +5 more sources

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

A feasibility study for quantitative assessment of cerebrovascular malformations using flutriciclamide ([18F]GE-180) PET/MRI

Frontiers in Medicine, 2023
AimNeuroinflammation plays a key role in both the pathogenesis and the progression of cerebral cavernous malformations (CCM). Flutriciclamide ([18F]GE-180) is a translocator protein (TSPO) targeting positron emission tomography (PET) tracer, developed ...
Sally Ji Who Kim, Sally Ji Who Kim, Janine M. Lupo, Yicheng Chen, Miguel H. Pampaloni, Henry F. VanBrocklin, Jared Narvid, Helen Kim, Youngho Seo   +8 more
doaj   +1 more source

Noninvasive PET Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering [PDF]

, 2016
Transplantation of human muscle precursor cells (hMPCs) is envisioned for the treatment of various muscle diseases. However, a feasible noninvasive tool to monitor cell survival, migration, and integration into the host tissue is still missing. METHODS:
Ametamey, Simon M., Betzel, Thomas, Dinulovic, Ivana, Eberli, Daniel, Handschin, Christoph, Haralampieva, Deana, Krämer, Stefanie D., Salemi, Souzan, Schibli, Roger, Stoelting, Meline, Sulser, Tullio   +10 more
core   +2 more sources

The Applications of Corrected Standardized Uptake Values in the Diagnosis of Peripheral Lung Lesions

Medicine, 2015
Fluorine 18-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) imaging has been widely used to diagnose many types of tumors. However, many factors can affect the accuracy of standardized uptake values (SUVs). In this study, we aimed to explore the applications of corrected SUVs in the diagnosis of peripheral solitary ...
Ming Ming, Wei Xue, Bin Shi, Fengyu Wu, Zhen G. Wang, Dacheng Li, Simin Liu   +6 more
openaire   +3 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Relations between the standardized uptake value of 18F-FDG-PET/CT and demographic, clinical, pathological, and radiological factors in lung cancer

Egyptian Journal of Chest Disease and Tuberculosis
Background FDG-PET/CT is considered a noninvasive method for mediastinal staging and functional assessment of lung cancer. Standardized uptake value maximum (SUVmax) estimates the activity of the tumor and its aggressiveness.
Hossam M. Abdel-Hamid
doaj   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Prognostic value of 18F-FDG PET/CT parameters and histopathologic variables in head and neck cancer

Brazilian Journal of Otorhinolaryngology, 2021
Introduction: 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters such as; maximum standardized uptake values, standard metabolic tumor volume and otal lesion glycosis are important prognostic biomarkers in cancers ...
Hale Aslan, Gul Cekin, Ercan Pinar, Mustafa Yazir, Abdulkadir Imre, Murat Songu, Akif Islek, Ibrahim Aladag, Ismail Semih Oncel   +8 more
doaj