Results 91 to 100 of about 2,450,081 (301)

INTERNAL CONTROL IN PUBLIC HEALTH SERVICES INSTITUTIONS [PDF]

open access: yesEconomica, 2017
Internal control has a special role in the efficient organization of the entity’s management. The components of this control in the institutions of public health service are determined by the specific character of these institutions and National ...
Ludmila FRUMUSACHI
doaj  

A Reconsideration of Environmental Federalism [PDF]

open access: yes
This paper provides a review and assessment of the debate over environmental federalism-the issue of the roles of different levels of government in environmental management.
Oates, Wallace
core  

Municipal Solid Waste Flow Control in the Post-Carbone World [PDF]

open access: yes, 1995
Garbage will always ultimately be the government\u27s problem. Evolving environmental standards and state and federal policies will continue to require reasoned responses from local governments and municipal solid waste flow control is a vital cog in ...
Abramowitz, David N., Peterson, Eric S.
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Setting Quality Standards for Environmental Management Policy: How Effective Is It? [PDF]

open access: yes
For a long time, the command-and-control approach has been in used in the Philippines as evidenced by the decreed minimum parameter for the acidity level of fresh waters.
Elazegui, Dulce D.
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Case Study: Vietnam Crab Fishery Prototype Gains Buy-in at Critical Points in the Supply Chain [PDF]

open access: yes, 2016
Vietnam's blue swimmer crab in Kien Giang province is threatened by overfishing. Mini-plant operators purchase juvenile and undersized crabs from fishers before the crabs have a chance to reproduce.

core  

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Standardization of management control/financial management systems utilized for the O&M, NR appropriation.

open access: yes, 1985
This thesis provides an overview of the management control and financial management systems currently utilized within the Naval Reserve Claimancy for management of the Operation and Maintenance, Naval Reserve (0&M,NR) Appropriation. An analysis of these systems and identification of control and performance weaknesses resulting from their utilization ...
Grieninger, Terry Merle.   +1 more
openaire   +1 more source

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