Results 61 to 70 of about 121,900 (274)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Parameter Identifiability and Redundancy: Theoretical Considerations [PDF]

, 2010
Background - Models for complex biological systems may involve a large number of parameters. It may well be that some of these parameters cannot be derived from observed data via regression techniques.
Wolfgang F Heidenreich, Little, Mark, Little Mark P., Li Guangquan, Mark P. Little, Li, Guangquan, Wolfgang F. Heidenreich, Heidenreich, Wolfgang, Mark P Little, Heidenreich Wolfgang F., Guangquan Li   +10 more
core   +2 more sources

Maternal depression across childhood and offspring young adult depression and anxiety: Testing adolescent emotion dynamics as transdiagnostic mechanisms

JCPP Advances, EarlyView.
Abstract Background Early exposure to maternal depression can increase risk for offspring mental health problems across the lifespan. Less is known about the transdiagnostic pathways through which maternal depression influences offspring mental health risk in young adulthood.
Gabrielle R. Rinne, Blakely L. Berryhill, Caroline M. Chandler, Jennifer A. Somers   +3 more
wiley   +1 more source

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

Modelling Critical Impeding Factors of Gamification Adoption: An ISM‐MICMAC Analysis

Global Business and Organizational Excellence, EarlyView.
ABSTRACT Gamification is a transformative technology that attracts consumers and motivates them toward desired actions through fun and engagement. Despite its growing popularity and influence on user behavior, gamification faces significant challenges in acceptance and implementation due to behavioral, technological, economic, and regulatory factors ...
Wamika Sharma, Dinesh Kumar, Aastha Verma, Rodney Lim, Garima Gupta   +4 more
wiley   +1 more source

Maxillomandibular Advancement Outcomes in Obstructive Sleep Apnea by Age and Gender

The Laryngoscope, EarlyView.
This systematic review and meta‐analysis of 36 studies (608 patients) found that maxillomandibular advancement significantly improves polysomnographic, cephalometric, and subjective measures of obstructive sleep apnea across both sexes and throughout the lifespan. Odds of surgical cure decline roughly 3% per year of age.
Matthew O. Herbst, Lucas C. Licaj, Ethan M. Kallenberger, Shaun A. Nguyen, Courtney Chou, Allen Huang, Emily A. Brennan, Mohamed Abdelwahab   +7 more
wiley   +1 more source

Markov-Driven Reliability Improvement in Duplex and Triplex Standby Architectures With Variable Failure and Repair Rates

Journal of Computer Networks and Communications
To enhance the reliability of industrial wireless sensor networks (IWSNs), this study develops a state-based continuous-time Markov model for duplex and triplex architectures equipped with warm and cold standby backup sensors.
Ahmadreza Zamani, Mohammad Ali Pourmina, Ramin Shaghaghi Kandovan   +2 more
doaj   +1 more source

Reliability assessment for Modular Multilevel Converters using Monte Carlo Simulations

International Journal of Electrical Power & Energy Systems
Modular Multilevel Converters (MMCs) offer significant advantages in the medium to high-voltage settings. The modular architecture of MMCs allows for redundant submodules (SMs) to improve overall reliability.
Miad Ahmadi, Aditya Shekhar, Pavol Bauer
doaj   +1 more source

A Mathematical Model for Solving a Multi Objective Choice of Redundancy Allocation Strategy Problem by Optimizing Reliability for K out of N Systems [PDF]

چشم‌انداز مدیریت صنعتی, 2015
The present paper is aimed to investigate a Redundancy Allocation Problem (RAP) to maximize the reliability and minimize the costs for a K-out-of-Nsystem.
Maghsoud Amiri, Soheil Azizi Boroujerdi, Seyed Hamed Pourbakhsh   +2 more
doaj  

A Study on the Distribution Characteristics of Salinity and Nutrients and the Migration Mechanism of Soil Salt in the Delingha Saline‐Alkali Soil Profile of the Qaidam Basin

Land Degradation &Development, EarlyView.
ABSTRACT Soil salinization negatively impacts the economic development and ecological environment, particularly in the arid and semiarid regions of China. The Qaidam Basin constitutes a major distribution area of saline‐alkali land in the country. However, the distribution patterns of salinity and nutrients within soil profiles and the underlying salt ...
Hongpan Xue, Chenyu Wang, Yiyan Chen, Binkai Li, Aiyin Cheng, Hongyu Li, Bo Dong, Xiuyun Min, Haicheng Wei   +8 more
wiley   +1 more source