Results 131 to 140 of about 291,764 (285)
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
The Battle of Passchendale: The Experiences of Lieutenant Tom Rutherford, 4th Battalion, Canadian Mounted Rifles [PDF]
, 2012 For a man who experienced many battles, 26 October 1917 was a pivotal day for Lieutenant Tom Rutherford. Destined to have a long and distinguished career, his experience that day, in many ways, would shape his military character and strengthen his ...
Adair, Jason, Rutherford, Tom
core +1 more source
تحقیقات جنگل و صنوبر ایران, 2007 The main objective of this study which was conducted in an intact stand of the experimental Kheiroudkenar forest (Chelir district), was to examine the ecological importance of dead trees followed by it’s impact on natural regeneration of the forest. In this study the seedlings around dead trees were recorded in a 50 ha stand, where the dead trees were ...
Eslam Zolfeghari +2 more
openaire +1 more source
Advanced Science, EarlyView.This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li +7 more
wiley +1 more source
Remote sensing applications to forest vegetation classification and conifer vigor loss due to dwarf mistletoe [PDF]
Criteria was established for practical remote sensing of vegetation stress and mortality caused by dwarf mistletoe infections in black spruce subboreal forest stands.
Douglass, R. W. +2 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
On the Origins of Toughness in Corymbia calophylla (Marri Tree) Nuts
Advanced Science, EarlyView.We uncover the natural toughening mechanisms of the marri nut, including fiber pullout, crack deflection, and a viscoelastic matrix, which enable exceptional energy absorption and ductility comparable to Teflon, with an elastic modulus similar to acrylic.
Wegood M. Awad +7 more
wiley +1 more source
Advanced Science, EarlyView.This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia +5 more
wiley +1 more source
Advanced Science, EarlyView.We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun +5 more
wiley +1 more source
Advanced Science, EarlyView.This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou +17 more
wiley +1 more source