Staphylococcal Infections and Neonatal Skin: Data from Literature and Suggestions for the Clinical Management from Four Challenging Patients [PDF]
Antibiotics, 2023 Staphylococcal infections in neonates might be associated with skin blistering since early antibiotic therapy has been shown to limit infection spread and positively influence outcomes; therefore, neonatologists should be aware of these conditions.
Domenico Umberto De Rose +8 more
doaj +3 more sources
The treatment of resistant staphylococcal infections [version 1; peer review: 3 approved] [PDF]
F1000Research, 2020 Staphylococcus aureus of the many staphylococcal species is the most common cause of both skin and soft tissue infection and severe staphylococcal infections including Staphylococcus aureus bacteremia (SAB).
Joseph John Jr
doaj +3 more sources
Neonatal Host Defense against Staphylococcal Infections [PDF]
Clinical and Developmental Immunology, 2013 Preterm infants are especially susceptible to late-onset sepsis that is often due to Gram-positive bacterial infections resulting in substantial morbidity and mortality. Herein, we will describe neonatal innate immunity to Staphylococcus spp.
Melanie R. Power Coombs +2 more
doaj +3 more sources
Exebacase: A Novel Approach to the Treatment of Staphylococcal Infections. [PDF]
Drugs R D, 2022 Lysins are bacteriophage-derived enzymes that degrade essential components of bacteria. Exebacase (Lysin CF-301) is an attractive antimicrobial agent because it demonstrates rapid bacteriolytic activity against staphylococcal species, including ...
McCarthy MW.
europepmc +2 more sources
Orthopaedic Implant-Associated Staphylococcal Infections: A Critical Reappraisal of Unmet Clinical Needs Associated with the Implementation of the Best Antibiotic Choice. [PDF]
Antibiotics (Basel), 2022 Infections associated with orthopaedic implants represent a major health concern characterized by a remarkable incidence of morbidity and mortality. The wide variety of clinical scenarios encountered in the heterogeneous world of infections associated ...
Gatti M +9 more
europepmc +2 more sources
Maternal-Fetal Perinatal Transmission of Staphylococcal Infections: A Report of Two Neonates [PDF]
Case Reports in Pediatrics, 2020 Staphylococcal infection in terms of fetus is rare and is associated with either maternal staphylococcal sepsis or colonization that leads to vertical transmission. Antenatal invasive procedures are a recognized risk factor.
V. Thadchanamoorthy, Kavinda Dayasiri
doaj +2 more sources
Staphylococcal Infections: Host and Pathogenic Factors [PDF]
Microorganisms, 2021 In 1880, the Scottish surgeon Sir Alexander Ogston first described staphylococci in pus from a surgical abscess in a knee joint: “The masses looked like bunches of grapes” [...]
Rajan P. Adhikari
doaj +2 more sources
Drug repurposing for the treatment of staphylococcal infections. [PDF]
Curr Pharm Des, 2015 The development and approval of new antimicrobials capable of being used to treat infections caused by multidrug-resistant pathogens has not kept pace with the rapid emergence of bacterial resistance.
Thangamani S +3 more
europepmc +2 more sources
Repurposing ebselen for treatment of multidrug-resistant staphylococcal infections. [PDF]
Sci Rep, 2015 Novel antimicrobials and new approaches to developing them are urgently needed. Repurposing already-approved drugs with well-characterized toxicology and pharmacology is a novel way to reduce the time, cost and risk associated with antibiotic innovation.
Thangamani S, Younis W, Seleem MN.
europepmc +2 more sources
Antimicrobial peptides and peptidomimetics - potent therapeutic allies for staphylococcal infections. [PDF]
Curr Pharm Des, 2015 The pervasiveness of bacterial resistance to conventional antibiotics, particularly those associated with staphylococcal infections, has become a global epidemic. However, research involving antimicrobial peptides (AMPs) and their synthetic analogues has
Mohammad H, Thangamani S, Seleem MN.
europepmc +2 more sources