Results 101 to 110 of about 62,495 (291)

Interface Wettability Transition‐Driven Drug Release and Dual‐Phase Functionalization in Implant Abutment

Advanced Science, EarlyView.
A temporally controlled drug release coating is developed for abutments using a superhydrophobic coating self‐assembled on mesoporous silica. This surface provides sequential functionality: initial contamination resistance through non‐wetting, followed by controlled drug release via wettability transition.
Zhongchao Wang, Liang Shi, MingXia Li, Xiao Han, Jinghan Wang, Guangping Wang, Dan Zou, Bingyang Lu, Liyuan Fan   +8 more
wiley   +1 more source

Population Pharmacokinetic and Pharmacodynamic Analysis for Maximizing the Effectiveness of Ceftobiprole in the Treatment of Severe Methicillin-Resistant Staphylococcal Infections. [PDF]

Microorganisms, 2023
Cojutti PG, Giuliano S, Pascale R, Angelini J, Tascini C, Viale P, Pea F.   +6 more
europepmc   +1 more source

Non-staphylococcal infections of cardiac implantable electronic devices

, 2010
Background. The number of infections of cardiac implantable electronic devices (CIED) continues to escalate out of proportion to the increase rate of device implantation. Staphylococcal organisms account for 70% to 90% of all CIED infections.
Viola, George M
core  

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Epidemiology of community-onset Staphylococcus aureus infections in pediatric patients: an experience at a Children's Hospital in central Illinois

BMC Infectious Diseases, 2009
Background The nation-wide concern over methicillin-resistant Staphylococcus aureus (MRSA) has prompted many clinicians to use vancomycin when approaching patients with suspected staphylococcal infections.
Gray Barry M, Mankin Peggy, Aldag Jean C, Mongkolrattanothai Kanokporn   +3 more
doaj   +1 more source

TLR2 mediates recognition of live Staphylococcus epidermidis and clearance of bacteremia

, 2010
Background: Staphylococcus epidermidis (SE) is a nosocomial pathogen that causes catheter-associated bacteremia in the immunocompromised, including those at the extremes of age, motivating study of host clearance mechanisms. SE-derived soluble components
Gallington, LC, Levy, O., Stoler-Barak Liat, Currie, A.J., Golenbock Douglas T., Golenbock, D.T., Melanie R Power Coombs, Otto, M, Gallington, Leighanne C., Burgner David, Levy, Ofer, Power Coombs, Melanie R., Richmond Peter, Currie, AJ, Douglas T Golenbock, Andrew J Currie, Power Coombs, M.R., Gallington, L.C., Strunk, Tobias, Stoler-Barak, L, Burgner, D., Burgner, D, Leighanne C Gallington, Golenbock, DT, Otto, Michael, Power Coombs Melanie R., Otto Michael, Currie, Andrew J., Richmond, P., Levy Ofer, Ofer Levy, Strunk Tobias, Otto, M., Liat Stoler-Barak, Tobias Strunk, Stoler-Barak, L., Burgner, David, Currie Andrew J., Richmond, Peter, Levy, O, Strunk, T, David Burgner, Coombs, MRP, Stoler-Barak, Liat, Peter Richmond, Strunk, T., Michael Otto, Richmond, P, Golenbock, Douglas T., Gallington Leighanne C.   +49 more
core   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Targeting staphylococcal bone infections

MedComm – Biomaterials and Applications, 2023
Zhang Xiangchun, Xulin Hu, Hongping Chen
doaj   +1 more source

Exebacase: A Novel Approach to the Treatment of Staphylococcal Infections. [PDF]

Drugs R D, 2022
McCarthy MW.
europepmc   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source