Results 161 to 170 of about 59,058 (298)

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

open access: yesAdvanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal   +3 more
wiley   +1 more source

Chromatic‐Zone Mapping for Rapid Discovery of Antibacterial Alloys with Nanostructured Surfaces

open access: yesAdvanced Science, EarlyView.
A high‐throughput parallel chromatic‐zone screening strategy that enables the simultaneous screening of alloy composition and surface structure. Ultimately linking surface color, composition, and morphology with antimicrobial performance enables the screening and prediction of color zones, thereby reducing characterization requirements by 90% and ...
Qiu‐Yu Zhao   +8 more
wiley   +1 more source

Usefulness of a hub and spoke TDM-guided expert clinical pharmacological advice program of dalbavancin for optimizing very long-term curative or suppressive treatment of chronic staphylococcal infections. [PDF]

open access: yesAntimicrob Agents Chemother
Cojutti PG   +19 more
europepmc   +1 more source

An unusual association of disseminated staphylococcal infection in dengue fever

open access: diamond, 2021
Sruthi Haridas   +5 more
openalex   +2 more sources

DNA‐Inspired Multi‐Functional Double‐Cross‐Linking Self‐Healing Hydrogel Promotes the Healing of Diabetic Wounds

open access: yesAdvanced Science, EarlyView.
A self‐healing hydrogel crosslinked with dynamic nucleobase‐mimetic bonds delivers curcumin‐loaded exosomes. It promotes diabetic wound healing via a synergistic combination of antibacterial, anti‐inflammatory, pro‐angiogenic, and immunomodulatory mechanisms, providing a comprehensive therapeutic approach.
Pu Yang   +7 more
wiley   +1 more source

Compartmentalization and Aggregation of Biomolecular Condensates in Crowded Hydrogels for Enhanced Nucleic Acid Diagnosis

open access: yesAdvanced Science, EarlyView.
A cell‐mimetic hydrogel compartment is proposed to enhance the efficiency of enzymatic reactions. The naturally porous structure of a crowded hydrogel can simulate the intracellular microenvironment, promoting the aggregation of biomolecules and activity of DNA polymerase through excluded volume effects and compartmentalization.
Fangbin Xiao   +3 more
wiley   +1 more source

MEndoB, a chimeric lysin featuring a novel domain architecture and superior activity for the treatment of staphylococcal infections. [PDF]

open access: yesmBio
Roehrig C   +13 more
europepmc   +1 more source

Host factors that contribute to recurrent staphylococcal skin infection

open access: green, 2015
Christopher P. Montgomery   +2 more
openalex   +1 more source

Electrosensitive Heterogeneous Short Fibers via Acousto‐Electric Coupling for Sequential Bone Regeneration in Infectious Defects

open access: yesAdvanced Science, EarlyView.
Electrosensitive heterogeneous short fibers can accurately respond to ultrasonic field regulation through the synergistic interaction of piezoelectric and conductive dual elements. At an ultrasound intensity of 1.5 W cm−2, it can effectively activate bacterial peroxisome and necrotic apoptotic pathway and promote bacterial apoptosis.
Xiaoyu Han   +11 more
wiley   +1 more source

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