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Despite recent scientific advances in diagnosis and treatment of human infections, bacterial infections continue to affect human health. The rate of morbidity and mortality caused by staphylococcal infections remains high and continues to be a threat to
Corina M. CRISAN+5 more
doaj +1 more source
Accepting higher morbidity in exchange for sacrificing fewer animals in studies developing novel infection-control strategies. [PDF]
Preventing bacterial infections from becoming the leading cause of death by the year 2050 requires the development of novel, infection-control strategies, building heavily on biomaterials science, including nanotechnology.
Busscher, Henk J.+16 more
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Background The evidence supporting rifampin combination therapy in prosthetic joint infections (PJI) is limited due to the lack of controlled studies.
Ø. E. Karlsen+10 more
semanticscholar +1 more source
Effective elimination of Staphylococcal contamination from hospital surfaces by a bacteriophage-probiotic sanitation strategy: a monocentric study. [PDF]
Persistent contamination of hospital surfaces and antimicrobial resistance (AMR) are recognized major causes of healthcare-associated infections (HAI). We recently showed that a probiotic-based sanitation (PCHS) can stably decrease surface pathogens and ...
BISI, Matteo+6 more
core +1 more source
Implicated in more than 60% of bone and joint infections (BJIs), Staphylococci have a particular tropism for osteoarticular tissue and lead to difficult-to-treat clinical infections.
Yousef Maali+16 more
doaj +1 more source
Understanding the Virulence of Staphylococcus pseudintermedius: A Major Role of Pore-Forming Toxins
Staphylococcus pseudintermedius is responsible for severe and necrotizing infections in humans and dogs. Contrary to S. aureus, the pathophysiological mechanisms involved in this virulence are incompletely understood.
Yousef Maali+21 more
doaj +1 more source
Staphylococcal Vaccine Antigens related to biofilm formation
The number and frequency of multidrug-resistant (MDR) strains as a frequent cause of nosocomial infections have increased, especially for Methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis, in part due to device-related infections.
Bahman Mirzaei+2 more
doaj +1 more source
Transfer of antibiotic resistance in Staphylococcus aureus [PDF]
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera.
Haaber, Jakob+2 more
core +1 more source
Increasing Skin Infections and Staphylococcus aureus Complications in Children, England, 1997-2006 [PDF]
During 1997-2006, general practitioner consultations for skin conditions for children
Alan P. Johnson+17 more
core +2 more sources
Clinical metagenomics of bone and joint infections: a proof of concept study
Bone and joint infections (BJI) are severe infections that require a tailored and protracted antibiotic treatment. Yet, the diagnostic based on culturing samples lacks sensitivity, especially for hardly culturable bacteria.
Etienne Ruppé+6 more
doaj +1 more source