Results 51 to 60 of about 881,385 (277)

Assessment of the current state of pharmaceutical development of anti-staphylococcal prophylactic drugs

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии
Infection caused by Staphylococcus aureus is the most common infection leading to the development of serious complications in humans. S. aureus is among the highly lethal bacteremia-associated pathogens with a mortality rate of approximately 18% in ...
Irina A. Builova   +4 more
doaj   +1 more source

Deciphering Mechanisms of Staphylococcal Biofilm Evasion of Host Immunity

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Biofilms are adherent communities of bacteria contained within a complex matrix. Although host immune responses to planktonic staphylococcal species have been relatively well-characterized, less is known regarding immunity to staphylococcal biofilms and ...
Mark L Hanke, Tammy eKielian
doaj   +1 more source

Immune-Based Anti-Staphylococcal Therapeutic Approaches

open access: yesMicroorganisms, 2021
Widespread methicillin-resistant Staphylococcus aureus (S. aureus) infections within community and healthcare settings are responsible for accelerated development of antibiotic resistance.
Bonggoo Park, George Y. Liu
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Staphylococcal infections among leukemic patients

open access: yesمجلة بغداد للعلوم, 2012
Staphylococcus are cause hospital community acquired infection and they are an important cause of health –care associated infection.The Coagulase positive Staphylococcus are Staphylococcus aureus which can implicated in toxic shock syndrome. Methicillin
Baghdad Science Journal
doaj   +1 more source

New Perspectives on Old and New Therapies of Staphylococcal Skin Infections: The Role of Biofilm Targeting in Wound Healing

open access: yesAntibiotics, 2021
Among the most common complications of both chronic wound and surgical sites are staphylococcal skin infections, which slow down the wound healing process due to various virulence factors, including the ability to produce biofilms.
Oriana Simonetti   +6 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Divergent Isoprenoid Biosynthesis Pathways in Staphylococcus Species Constitute a Drug Target for Treating Infections in Companion Animals

open access: yesmSphere, 2016
Staphylococcus species are a leading cause of skin and soft tissue infections in humans and animals, and the antibiotics used to treat these infections are often the same.
Ana M. Misic   +4 more
doaj   +1 more source

Staphylococcal decolonization to prevent surgical site infection: Is there a role in colorectal surgery?

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology, 2022
Objective: We implemented a preoperative staphylococcal decolonization protocol for colorectal surgeries if efforts to further reduce surgical site infections (SSIs). Design: Retrospective observational study. Setting: Tertiary-care, academic medical
Rasha Raslan   +7 more
doaj   +1 more source

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