Results 91 to 100 of about 675,207 (304)

Characterization and Comparison of 2 Distinct Epidemic Community-Associated Methicillin-Resistant Staphylococcus aureus Clones of ST59 Lineage. [PDF]

, 2013
Sequence type (ST) 59 is an epidemic lineage of community-associated (CA) methicillin-resistant Staphylococcus aureus (MRSA) isolates. Taiwanese CA-MRSA isolates belong to ST59 and can be grouped into 2 distinct clones, a virulent Taiwan clone and a ...
Götz, F, Wolfgang Hoffmann, Yhu-Chering Huang, Clemens Unger (454672), Wolfgang Hoffmann (30039), Huang Yhu-Chering, Unger, C, Chen Chih-Jung, Jodi A. Lindsay (119622), Lindsay, JA, Huang, YC, Clemens Unger, Yhu-Chering Huang (110834), Hoffmann Wolfgang, Jodi A Lindsay, Friedrich Götz (33134), Unger Clemens, Chih-Jung Chen (207116), Chih-Jung Chen, Lindsay Jodi A., Chen, CJ, Hoffmann, W, Götz Friedrich, Friedrich Götz   +23 more
core   +2 more sources

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

Advanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

Inflamatory Markers in Cows Affected by Subclinical Mastitis due to E.coli and Staphylococcus Infections [PDF]

Archives of Razi Institute
Investigating the concentrations of Serum Amyloid A (SAA), IL-6, and IL-8 in the serum during episodes of clinical and subclinical mastitis holds significant value.
Seyedeh Ommolbanin Ghasemian, Siamak Asri-Rezaei   +1 more
doaj   +1 more source

Rapid Multiplex Antimicrobial Resistance Profiling and Bacterial Identification by LAP‐MALDI Mass Spectrometry Biotyping

Advanced Science, EarlyView.
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair, Shabnam Iyer, Ian M. Jones, Rainer Cramer   +3 more
wiley   +1 more source

In vitro antimicrobial effect of palm oils rich in medium-chain fatty acids against mastitis-causing Gram-positive bacteria

Czech Journal of Animal Science, 2019
Various pathogens causing mastitis in dairy cattle are of serious concern due to their increasing antibacterial resistance and potential transmission to other cows, calves, and the environment, especially through the milking process.
Klára Laloučková, Lucie Malá, Paula Slaničková, Eva Skřivanová   +3 more
doaj   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Biologically Active Substances from Marine Hydrobionts with Antibacterial Activity in Composition of New Wound Dressings

Антибиотики и Химиотерапия, 2020
The data on the experimental study of the efficacy of the gel wound dressings based on chitosan and calcium alginate containing bioactive substances from marine hydrobionts with complex therapeutic action (sulfated polysaccharides from brown algae ...
T. A. Kuznetsova, N. N. Besednova, T. S. Zaporozhets, N. N. Kovalev, V. V. Usov, A. B. Zemlyanoi   +5 more
doaj  

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

A Microcapsule‐Integrated smRandom‐seq Platform Enables Fixation‐Free Single Microbe RNA Sequencing

Advanced Science, EarlyView.
We developed a microcapsule‐integrated high‐throughput fixation‐free single‐microbe RNA‐seq workflow in which microbes are encapsulated in aqueous two‐phase microcapsules for physical confinement of nucleic acids. This platform enables co‐encapsulation with barcoded beads for sequencing and reveals that fixation‐free processing enhances transcriptomic ...
Mengdi Song, Yuting Wang, Zhaolun Wang, Shunji Zhang, Zhengmin Tang, Yongcheng Wang   +5 more
wiley   +1 more source

Cell wall architecture and the role of wall teichoic acid in Staphylococcus aureus [PDF]

, 2013
The bacterium Staphylococcus aureus only synthesises peptidoglycan during cell division at the septum using a complex protein biosynthetic apparatus called the divisome.
Kent, V
core   +3 more sources