Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
Pet Birds as Potential Reservoirs of Antimicrobial-Resistant Bacteria in Digestive and Respiratory Infections. [PDF]
Crăciun S +7 more
europepmc +1 more source
Nucleotide‐detected solid‐state NMR has been applied to probe nucleotide conformations and dynamics during ATP hydrolysis using the dimeric P‐loop ATPase SmsC as a model protein. The different stages of ATP hydrolysis have been mimicked by ATP analogues for which different degrees of conformational heterogeneity have been observed. ABSTRACT Solid‐state
Nina Wehr +7 more
wiley +1 more source
<i>Staphylococcus aureus</i> in Dairy Cattle Milk: Prevalence, Risk Factors, and Antibiogram Profile in Gimbichu Town, Hadiya Zone. [PDF]
Gobe M +6 more
europepmc +1 more source
Precision Chemistry for Protein Lysine Modification
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley +1 more source
Disseminated Thoracic Methicillin-Resistant <i>Staphylococcus aureus</i> Infection Mimicking Tuberculosis in a Patient on Haemodialysis. [PDF]
MacCready ENA +5 more
europepmc +1 more source
Relay Approach: A Convergent Synthesis of Key Fragments en route to (+)‐Neosorangicin A
A selective synthesis of three key fragments of the antibiotically active (+)‐neosorangicin A is reported, providing a foundation for its convergent total synthesis and proof of strategy via a relay approach. ABSTRACT Herein, we report the synthesis of the three key fragments of the macrolide antibiotic (+)‐neosorangicin A, a compound exhibiting potent
Marvin Wenninger +6 more
wiley +1 more source
Bacteriological Profile and Antibiogram of Culture-Confirmed Orthopaedic Wound Infections in a Tertiary Care Hospital. [PDF]
Lahon P, Talukdar M.
europepmc +1 more source
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley +1 more source
Fluorometholone-antibiotic interactions in canine ocular bacteria: <i>in vitro</i> susceptibility changes in common corneal infection pathogens. [PDF]
Kim D, Jung JS, Park J, Park KM.
europepmc +1 more source

