Results 351 to 360 of about 1,193,518 (407)

Noncoding RNAs in Host–Microbiota Interaction

open access: yesAnimal Research and One Health, EarlyView.
The intricate interplay between gut microbiota and the host exerts a profound impact on host biological processes and disease development. This review highlights the pivotal role of noncoding RNAs (ncRNAs) in this interaction. Host ncRNAs regulate gene expression and microbiota composition, whereas microbial small RNAs (sRNAs) modulate host gene ...
Ziyi Zhao   +7 more
wiley   +1 more source

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

open access: yesAnimal Research and One Health, EarlyView.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao   +12 more
wiley   +1 more source

Investigation of antibacterial and anticancer activities of biosynthesized metal‐doped and undoped zinc oxide nanoparticles

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
Abstract Over the past 10 years, nanotechnology has emerged as a very promising technique for a wide range of biomedical applications. Green synthesized metal and metal oxide nanoparticles (NPs) are cheap, easy to produce in large quantities, and safe for the environment.
Kaan Şendal   +6 more
wiley   +1 more source

Design and Synthesis of Triazole‐Based p‐tert‐Butylcalix[4]Arene Conjugates and Evaluation of Their Antimicrobial, Antibiofilm, and Anti‐Quorum‐Sensing Activities

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Macrocyclic calix[n]arenes have many applications, with diverse structures that can easily be functionalized either on upper or lower rims, mostly to impart solubility and improve biological activities. In this study, triazole‐based p‐tert‐butylcalix[4]arene conjugates (AT10a and AT10b) and their p‐tert‐butylphenol analogs (AT10b and AT11b ...
Alfred Ngenge Tamfu   +2 more
wiley   +1 more source

First‐time cefuroxime target tissue concentrations in long‐lasting spine surgery: Continuous evaluation after repeated weight‐dosed administrations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Antimicrobial prophylaxis is central in preventing postoperative spine infections, yet knowledge on clinical target spine tissue concentrations remain limited. Current dosing regimens often involve fixed doses based on empirical knowledge, surrogate measures, non‐clinical evidence and methodology of variying quality.
Magnus Andreas Hvistendahl   +6 more
wiley   +1 more source

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