Results 161 to 170 of about 890,247 (348)

Novel determinants of antibiotic resistance : identification of mutated loci in highly methicillin-resistant subpopulations of methicillin-resistant Staphylococcus aureus

, 2014
This work was supported by a grant from the U.S. Public Health Service 2 RO1 AI457838-14 and by grant UL1 TR000043-07S1 from the National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH) Clinical and Translational ...
Kim, Choonkeun, Hermínia de Lencastre, Matthew T. J. Holden, Holden, Matthew T J, María Pardos de la Gándara, Tomasz, Alexander, Parkhill, Julian, de Lencastre, Hermínia, Alexander Tomasz, Stephen D. Bentley, Janina Dordel, Dordel, Janina, Pardos de la Gándara, María, Chung, Marilyn, Bentley, Stephen D, Marilyn Chung, Choonkeun Kim, Julian Parkhill   +17 more
core   +1 more source

Sodium Ascorbate‐Accelerated Gelling Hydrogels With Rapid Self‐Mineralized Capacity for Chronic Wounds

Advanced Science, EarlyView.
An immunoregulatory hydrogel based on sodium ascorbate (SA)‐accelerated gelation and in situ self‐mineralization is prepared here. Such a hydrogel is constructed by mixing benzaldehyde‐ and cyanoacetate‐functionalized dextran with silver nitrate (AgNO3) and SA, enabling the ultrafast solidification and in situ self‐mineralization of silver ...
Xiaoya Ding, Wei Yang, Wenzhao Li, Guifang Xu, Yuanjin Zhao   +4 more
wiley   +1 more source

STAPHYLOCOCCUS AUREUS RESISTENTE A LA METICILINA ADQUIRIDO EN LA COMUNIDAD

Revistas Argentina de Medicina, 2017
Introducción. Las infecciones por Staphylococcus aureus meticilinorresistente de origen comunitario son parte de las enfermedades emergentes del último tiempo. Objetivo.
Lucía Lamponi Tappatá, Pamela Mas, Ana Julia Altube, Danisa Dietrich, Marcos Petasny, Ana Laura Tomás, Sofía Martín, Martín Biaggioni, Gabriela Harguindeguy, Dina Pedersen   +9 more
doaj   +2 more sources

A Sprayable Nanoplatform Breaks the Vicious Cycle of Diabetic Wounds via Photoactivated Antioxidant and Drug Delivery

Advanced Science, EarlyView.
A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo, Yuanyuan Meng, Qixiang Gui, Xi‐Tao Yang, Yong Fan, Xiaodong Zhu   +5 more
wiley   +1 more source

Bone: The final frontier for penetration in chronic rhinosinusitis

Journal of Otolaryngology - Head and Neck Surgery, 2013
The superantigenic properties of Staphylococcus aureus have been implicated in increasing the inflammatory process in airway diseases. Local formation of IgE antibodies against staphylococcal enterotoxins by secondary lymphoid tissue in nasal polyps has ...
Rogério Pezato, Luciano Bottura, Rodrigo de Paula Santos, Richard Louis Voegels, Andre Luis Lacerda Bachi, Luis Carlos Gregório   +5 more
doaj   +1 more source

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, EarlyView.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

A shared population of epidemic methicillin-resistant Staphylococcus aureus 15 circulates in humans and companion animals

, 2014
This work was supported by a Medical Research Council Partnership grant (G1001787/1) held between the Department of Veterinary Medicine, University of Cambridge (M.A.H.), the School of Clinical Medicine, University of Cambridge (S.J.P.), the Moredun ...
Andrew S. Waller, Boag, A K, Waller, Andrew S., John J. Welch, Sharon J. Peacock, Holden, Matthew T G, Wilson, Katherine, Parkhill, J, Harrison, Ewan M, Holmes, M A, Mark A. Holmes, Waller, Andrew S, Harris, Simon R., Welch, John J., Loeffler, Anette, Harris, Simon R, Boag, Amanda K, Holden, Matthew T. G., Peacock, Sharon J., Lucy A. Weinert, Harris, S R, Anette Loeffler, Morgan, F J E, Holden, M T G, Harrison, E M, Gavin K. Paterson, Paterson, Gavin; id_orcid, Katherine Wilson, Harrison, Ewan M., Ewan M. Harrison, Weinert, Lucy A., Peacock, Sharon J, Paterson, Gavin K., Fiona J. E. Morgan, Weinert, Lucy A, Loeffler, A, Waller, A S, Welch, J J, Simon R. Harris, Peacock, S J, Morgan, Fiona J E, Paterson, G K, Julian Parkhill, Amanda K. Boag, Matthew T. G. Holden, Paterson, Gavin K, Parkhill, Julian, Weinert, L A, Boag, Amanda K., Wilson, K, Welch, John J, Morgan, Fiona J. E., Holmes, Mark A, Holmes, Mark A.   +53 more
core   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

Clinical Microbiology Reviews, 2015
S. Tong, Joshua S. Davis, E. Eichenberger, T. Holland, V. Fowler   +4 more
semanticscholar   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source