Results 221 to 230 of about 600,038 (258)

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source

A novel rapid host cell entry pathway determines the intracellular fate of <i>Staphylococcus aureus</i>. [PDF]

Elife
Rühling M, Schmelz F, Ulbrich K, Schumacher F, Wolf J, Pfefferle M, Priester M, Moldovan A, Knoch N, Iwanowitsch A, Kappe C, Paprotka K, Kleuser B, Arenz C, Fraunholz MJ.   +14 more
europepmc   +1 more source

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Pan-Ras-In-1 triggers cell wall lysis to eradicate <i>Staphylococcus aureus</i>. [PDF]

iScience
Han W, Guo Y, Shen L, Huang Y, Yuan X, Wang B, Yang C, Hu R, Shang Y, Yu F.   +9 more
europepmc   +1 more source

Phosphonomethyl (Thio)Phosphonamidite Reagents for the Construction of Phosphonylmethyl Phosphono(Di)Thioate Mono‐ and Diesters

Chemistry – A European Journal, EarlyView.
A set of new phosphonomethyl (thio)phosphonamidite reagents is introduced to generate unprecedented pyrophosphate mimetics. The versatile P(III)‐P(V) reagents allow for the construction of various pyrophosphate isosteres, and the applicability of the chemistry is illustrated in the assembly of a diverse set of stabilized CDP‐glycerol and CDP‐ribitol ...
Pascal Balić, Roy Steneker, Gijsbert A. van der Marel, Jeroen D. C. Codée, Dmitri V. Filippov   +4 more
wiley   +1 more source

Complexity and comorbidities: critical considerations for methicillin-resistant Staphylococcus aureus bacteraemia outcomes in the Northern Territory. [PDF]

Intern Med J
Shakeel N.
europepmc   +1 more source

The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin

Clinical Pharmacology &Therapeutics, EarlyView.
Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul, Waseem Mujahed, Ibrahim Idries, Maor Wanounou, Meir Bialer, Yoseph Caraco   +5 more
wiley   +1 more source

Biocontrol of Staphylococcus aureus in dairy products using lytic bacteriophage UHP46: efficacy in milk, cheese, and yogurt. [PDF]

Braz J Microbiol
Najeeb S, Khan I, Muhammad J, Jahangir M, Abbas A, Ullah A, Khan A, Miskeen S.   +7 more
europepmc   +1 more source

Research progress on T-cell responses in <i>Staphylococcus aureus</i> infections. [PDF]

Front Microbiol
Li X, Wang R, Yan W, Guan J, Pan H, Wang B.   +5 more
europepmc   +1 more source