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Early and Accurate Pathogen Identification Based on mNGS: Key to Timely Therapy for Mycoplasma Prosthetic Joint Infection

open access: yesOrthopaedic Surgery, Volume 17, Issue 7, Page 1995-2003, July 2025.
Prior invasive urinary catheterization represents a significant risk factor for Mycoplasma PJI. The synergistic use of mNGS, optimized culture methods, and 16S rRNA PCR enables early detection of Mycoplasma. The multimodal diagnostic approach significantly enhances Mycoplasma identification accuracy, minimizes diagnostic oversights, and provides ...
Zhenyuan Lin   +8 more
wiley   +1 more source

Heritable Tissue‐Specific Gene Expression Associates With Chronic Wound Microbial Species

open access: yesWound Repair and Regeneration, Volume 33, Issue 4, July/August 2025.
ABSTRACT The reasons for interpatient variability in chronic wound microbiome composition are thought to be complex but are poorly known. To investigate how patients' genetically regulated tissue expression may influence chronic wound bacterial composition, we performed a microbiome‐transcriptome‐wide association study.
Khalid Omeir   +10 more
wiley   +1 more source

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