Results 51 to 60 of about 1,177 (238)

Star Architecture Spreads in Europe: Culture-Led Waterfront Projects Between 1990 and 2015

open access: yes, 2020
This contribution is the first attempt to provide a systematic study of the spread of culture-led waterfront projects in Europe that are designed (or inclusive of substantial elements designed) by major transnational firms, often labelled as star ...
Akhavan, Mina   +3 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Library plans : architects watching the council

open access: yes, 1930
Architects may ban the Johannesburg City Library Competition if the Council's draft conditions are not ...
Unknown
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Museum projects of the star-architects

open access: yes, 2014
In the 1980’s the amount of new museum constructions started raising suddenly and the most famous pre-existing institutions began to create its external branches in distant locations. Crowning achievement of this process was a grand opening of Guggenheim
Klimek, A.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Introduction: Star Architecture in and Across Cities in Europe

open access: yes, 2020
In the last three decades, urban decision makers in the Western world increasingly promote and build exceptional architecture projects such as iconic museums, spectacular infrastructures or public spaces not only for branding their city image and ...
Alaily-Mattar, Nadia   +2 more
core   +1 more source

APPLICATION OF GREEN BUILDING DESIGN STRATEGIES IN THE DESIGN OF A FIVE-STAR HOTEL IN IKOYI, LAGOS [PDF]

open access: yes, 2023
In the course of their regular operations, hotels incur significant operating and maintenance costs. In Nigeria, the production of power for heating and cooling, electricity, and water use consumes the majority of hotel earnings.
Covenant University, Theses   +1 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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