Results 161 to 170 of about 45,046 (289)
Planet formation and disc dynamics in stellar clusters and misaligned binary systems
, 2009 PhDIn this thesis I investigate the formation and dynamics of planets and protoplanetary discs, subject to external gravitational perturbations.
Fragner, Moritz Matthias
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Lone black holes promise fresh insights into the fates of massive stars. [PDF]
Proc Natl Acad Sci U S ACroswell K.
europepmc +1 more source
"Should I surrender?": performing and interrogating female virginity in Hollywood films 1957-64 [PDF]
The twin topics of interest to this thesis are the figure of the desirous virgin, as she appeared in Hollywood films around the cusp of the 1960s, and Doris Day, during the later evolution of her star persona around the time of Pillow Talk (Michael ...
Jeffers, Tamar Elizabeth Louise
core
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Medicine, Duty and Disaster: The Lives and Last Hours of RMS Titanic's Surgeons. [PDF]
Ann Surg OpenMcKenna ME, Ross FL.
europepmc +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Protocol for targeted peripheral adeno-associated viral vector transduction of the intradental neurons in mice. [PDF]
STAR ProtocLiu LY +3 more
europepmc +1 more source