Results 71 to 80 of about 164,992 (306)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Exploring the Origin of Stars on Bound and Unbound Orbits Causing Tidal Disruption Events

open access: yesThe Astrophysical Journal, 2023
Tidal disruption events (TDEs) provide a clue to the properties of a central supermassive black hole (SMBH) and an accretion disk around it, and to the stellar density and velocity distributions in the nuclear star cluster surrounding the SMBH ...
Shiyan Zhong   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Star Trek : Arbeitsbibliographie

open access: yes, 2010
Eine erste Fassung der folgenden Bibliographie haben wir in: Faszinierend! STAR TREK und die Wissenschaften. 2. (hrsg. v. Nina Rogotzki [...]. Kiel: Ludwig 2003, S.
Rogotzki, Nina, Wulff, Hans Jürgen
core  

Relativistic Motion of the Test Body in Photogravitational Field of Star: Application to the Solar System [PDF]

open access: yes, 2014
The regularities of the motion for every test body in photogravitational field of a star, which can significantly di˙er from the regularities of motion of a body in gravitational field, have been obtained. The following e˙ects of STR and GTR to the terms of
Ryabushko, A. P.   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Hyperneutron Stars from an Ab Initio Calculation

open access: yesThe Astrophysical Journal
The equation of state (EOS) of neutron matter plays a decisive role in understanding the neutron star properties and the gravitational waves from neutron star mergers. At sufficient densities, the appearance of hyperons generally softens the EOS, leading
Hui Tong   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy