Results 231 to 240 of about 342,420 (348)

Light element abundance inhomogeneities in globular clusters: probing star formation and evolution in the early Milky Way [PDF]

, 1994
Michael M. Briley, R. A. Bell, J. E. Hesser, Graeme H. Smith   +3 more
openalex   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

Epigenetic instability and hypofunctionality of fetal Tregs allow a permissive regulatory environment for T effector memory maturation. [PDF]

Proc Natl Acad Sci U S A
Leong JY, McGovern N, Mishra A, Wasser M, Kumar P, Tay SH, Nur Hazirah S, Yeo JG, Tan XQ, Sutamam N, Azman FN, Chua CJH, Chen PZ, Ally F, Dutertre CA, Ramakrishna L, Poh SL, Xie L, Fan Y, Donner C, Papadopoulou M, Vermijlen D, Arkachaisri T, Chan JKY, Ginhoux F, Albani S.   +25 more
europepmc   +1 more source

Theoretical zero-age main sequences applied to the Pleiades, Praesepe, and Hyades star clusters

, 1984
Don A. VandenBerg, Terry Bridges
openalex   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Tidal tail identification and detailed analysis of the open star cluster King 13 using Gaia DR3 and 2MASS. [PDF]

Sci Rep
Ahmed NM, Darwish MS.
europepmc   +1 more source

Stromagenesis and cancer‐associated fibroblast heterogeneity in primary tumors and metastasis: focus in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
Cancer‐associated fibroblasts (CAFs) play different roles in NSCLC progression and metastasis. Their heterogeneous origins and phenotypes shape the tumor microenvironment and influence metastatic spread. This review highlights NSCLC CAF subtypes, their potential cellular sources, and their differential distribution across primary tumors and distant ...
Alejandro Bernardo, Natalia Díaz‐Valdivia, Patricia Fernández‐Nogueira, Jordi Alcaraz   +3 more
wiley   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Genome analysis of <i>Neisseria gonorrhoeae</i> in Norway, 2016-2023, reveals shifting epidemiology in the wake of the COVID-19 pandemic. [PDF]

Microb Genom
Alfsnes K, Osnes MN, Gilboe HM, Eldholm V, Caugant DA.   +4 more
europepmc   +1 more source