Results 271 to 280 of about 71,711 (296)

Moderators and mediators of pain and function outcomes in a new service delivery model for management of knee osteoarthritis in primary care (PARTNER): Secondary exploratory analysis of a randomized controlled trial

Arthritis Care &Research, Accepted Article.
Objective Explore moderators and mediators influenced changes in pain and function in people with knee osteoarthritis (OA) receiving a new model of primary care service delivery (PARTNER), at 12 months (ACTRN12617001595303). Methods Secondary analyses of a cluster randomized controlled trial comparing PARTNER to usual general practitioner‐delivered ...
Abdolhay Farivar, Jocelyn L Bowden, Kim L Bennell, Andrew M Briggs, Stephen J Bunker, Rana S Hinman, Thorlene Egerton, Simon D French, Marie Pirotta, Karen Schuck, Venkatesha Venkatesha, Nicholas A Zwar, David J Hunter   +12 more
wiley   +1 more source

Neisseria gonorrhoeaeLIN codes: a Robust, Multi-Resolution Lineage Nomenclature

Unitt A, Krisna M, Parfitt KM, Jolley KA, Maiden MC, Harrison OB.   +5 more
europepmc   +1 more source

The brittle star genome illuminates the genetic basis of animal appendage regeneration. [PDF]

Nat Ecol Evol
Parey E, Ortega-Martinez O, Delroisse J, Piovani L, Czarkwiani A, Dylus D, Arya S, Dupont S, Thorndyke M, Larsson T, Johannesson K, Buckley KM, Martinez P, Oliveri P, Marlétaz F.   +14 more
europepmc   +1 more source

Time trends and predictors of gout remission over six years

Arthritis Care &Research, Accepted Article.
Objectives This study aims to describe the trends in remission rates over six years of follow‐up among people with gout taking urate‐lowering therapy (ULT), and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES ...
Adwoa Dansoa Tabi‐Amponsah, Sarah Stewart, Greg Gamble, Lisa K Stamp, William J Taylor, Nicola Dalbeth   +5 more
wiley   +1 more source

Virtual patients inspired by multiomics predict the efficacy of an anti-IFNα mAb in cutaneous lupus. [PDF]

iScience
Hurez V, Gauderat G, Soret P, Myers R, Dasika K, Sheehan R, Friedrich C, Reed M, Laigle L, Riquelme MA, Aussy A, Chadli L, Hubert S, Desvaux E, Fouliard S, Moingeon P, PRECISESADS Clinical Consortium.   +16 more
europepmc   +1 more source

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

ACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi, Ennio Giulio Favalli, Gabriella Maioli, Elena Agape, Marzia Rossato, Matteo Paini, Adriana Severino, Barbara Vigone, Martina Biggioggero, Elena Trombetta, Roberto Caporali, Lorenzo Beretta   +11 more
wiley   +1 more source

A spatially resolved transcriptome landscape during thyroid cancer progression. [PDF]

Cell Rep Med
Liao T, Zeng Y, Xu W, Shi X, Shen C, Du Y, Zhang M, Zhang Y, Li L, Ding P, Hu W, Huang Z, Fung MHM, Ji Q, Wang Y, Li S, Wei W.   +16 more
europepmc   +1 more source

mKmer: an unbiased K-mer embedding of microbiomic single-microbe RNA sequencing data. [PDF]

Brief Bioinform
Mo F, Qian Q, Lu X, Zheng D, Cai W, Yao J, Chen H, Huang Y, Zhang X, Wu S, Shen Y, Bai Y, Wang Y, Jiang W, Fan L.   +14 more
europepmc   +1 more source

A genetically tractable branch of environmental Pedobacter from the phylum Bacteroidota represents a hotspot for natural product discovery. [PDF]

Sci Rep
Liu Y, Linares-Otoya L, Kersten C, Marner M, Mihajlovic S, Abdeldayem MH, Semmler S, Bletz MC, Vences M, Spohn M, Zumkeller CM, Schäberle TF.   +11 more
europepmc   +1 more source