Single-cell RNA sequencing uncovers cellular heterogeneity of granulosa cells and provides a signature for follicular development in chicken. [PDF]
Yu S, Shen X, Wang G, Liao J, Chen J.
europepmc +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source
Corrigendum to "Evaluating the performance of the PREDAC method in flu vaccine recommendations over the past decade (2013-2023)" [Virol. Sin. 40 (2025) 288-291]. [PDF]
Peng Y+8 more
europepmc +1 more source
Objective Our objective was to explore moderators and mediators influenced changes in pain and function in people with knee osteoarthritis (OA) receiving a new model of primary care service delivery (Optimizing Primary Care Management of Knee Osteoarthritis [PARTNER]), at 12 months (ACTRN: 12617001595303).
Abdolhay Farivar+12 more
wiley +1 more source
Cell-death pathways and tau-associated neuronal vulnerability in Alzheimer's disease. [PDF]
Lin G+25 more
europepmc +1 more source
Time Trends and Predictors of Gout Remission Over 6 Years
Objective This study aims to describe the trends in remission rates over 6 years of follow‐up among people with gout taking urate‐lowering therapy (ULT) and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial ...
Adwoa Dansoa Tabi‐Amponsah+5 more
wiley +1 more source
Multi-omics analysis of the dynamic role of STAR+ cells in regulating platinum-based chemotherapy responses and tumor microenvironment in serous ovarian carcinoma. [PDF]
Lan H, Yan W, Huang X, Cui J, Hou H.
europepmc +1 more source
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE) but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment, and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung+6 more
wiley +1 more source
Combining nanobody labeling with STED microscopy reveals input-specific and layer-specific organization of neocortical synapses. [PDF]
Akter Y+5 more
europepmc +1 more source