Results 241 to 250 of about 392,769 (291)

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

The mean ages of S0 disks - Evidence for star formation 5 gigayears ago

, 1990
G. D. Bothun, Michael D. Gregg
openalex   +1 more source

Micro-CT analysis reveals porosity driven growth banding in Caribbean coral Siderastrea siderea. [PDF]

Sci Rep
Vincent J, Sheldrake T.
europepmc   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

An H-alpha survey of cluster spirals - Comparison of star formation in clusters and the field

, 1993
C. Moss, M. Whittle
openalex   +1 more source

Histological study of the effect of different hydration times of bone allograft and xenograft particles on the rate of bone formation in critical size defects in the rat calvarium. [PDF]

Int J Implant Dent
Lashkarizadeh N, Mohammadi M, Mohyadin Z, Kalantari M, Kakooei S, Karamoozian A.   +5 more
europepmc   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Dense molecular gas, star formation, and the CO to H2 conversion factor in nearby galaxies

, 1990
Leslie J. Sage, S. N. Shore, P. M. Solomon   +2 more
openalex   +1 more source

Two Leucobacter strains exert complementary virulence on Caenorhabditis including death by worm-star formation.

Curr Biol, 2013
Hodgkin J, Félix MA, Clark LC, Stroud D, Gravato-Nobre MJ.   +4 more
europepmc   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source