Results 151 to 160 of about 1,223,277 (388)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Molecular Star Formation Rate Indicators in Galaxies

, 2008
We derive a physical model for the observed relations between star formation rate (SFR) and molecular line (CO and HCN) emission in galaxies, and show how these observed relations are reflective of the underlying star formation law.
Andre P., Bernes C., Christopher K. Walker, Desika Narayanan, Lars Hernquist, Romeel Davé, Thomas J. Cox, Yancy Shirley   +7 more
core   +1 more source

REGULARITY UNDERLYING COMPLEXITY: A REDSHIFT-INDEPENDENT DESCRIPTION OF THE CONTINUOUS VARIATION OF GALAXY-SCALE MOLECULAR GAS PROPERTIES IN THE MASS-STAR FORMATION RATE PLANE [PDF]

, 2013
Star-forming galaxies (SFGs) display a continuous specific star formation rate (sSFR) distribution, which can be approximated by two log-normal functions: one encompassing the galaxy main sequence (MS), and the other a rarer, starbursting population ...
M. Sargent, M. Sargent, E. Daddi, M. Béthermin, H. Aussel, G. Magdis, H. Hwang, S. Juneau, D. Elbaz, E. D. Cunha   +9 more
semanticscholar   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Mass-metallicity relation explored with CALIFA I. Is there a dependence on the star-formation rate? [PDF]

, 2013
We studied the global and local ℳ-Z relation based on the first data available from the CALIFA survey (150 galaxies). This survey provides integral field spectroscopy of the complete optical extent of each galaxy (up to 2−3 effective radii), with a ...
S. Sánchez, S. Sánchez, F. Rosales-Ortega, B. Jungwiert, J. Iglesias-Páramo, J. Vílchez, R. Marino, C. Walcher, B. Husemann, D. Mast, A. Monreal-Ibero, R. C. Fernandes, E. Pérez, R. Delgado, R. García-Benito, L. Galbany, G. Ven, K. Jahnke, H. Flores, J. Bland-Hawthorn, Á. López-Sánchez, V. Stanishev, D. Miralles-Caballero, Á. D́ıaz, P. Sánchez-Blázquez, M. Mollá, A. Gallazzi, P. Papaderos, J. Gomes, N. Gruel, I. Pérez, T. Ruiz-Lara, E. Florido, A. D. Lorenzo-C'aceres, J. Méndez-Abreu, J. Méndez-Abreu, C. Kehrig, M. Roth, B. Ziegler, J. Alves, L. Wisotzki, D. Kupko, A. Quirrenbach, D. Bomans   +43 more
semanticscholar   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Learning the Universe: GalactISM Simulations of Resolved Star Formation and Galactic Outflows across Main-sequence and Quenched Galactic Environments

The Astrophysical Journal
We present a suite of six high-resolution chemodynamical simulations of isolated galaxies, spanning observed disk-dominated environments on the star-forming main sequence, as well as quenched, bulge-dominated environments.
Sarah M. R. Jeffreson, Eve C. Ostriker, Chang-Goo Kim, Jindra Gensior, Greg L. Bryan, Timothy A. Davis, Lars Hernquist, Sultan Hassan   +7 more
doaj   +1 more source

The Protostellar Luminosity Function

, 2011
The protostellar luminosity function (PLF) is the present-day luminosity function of the protostars in a region of star formation. It is determined using the protostellar mass function (PMF) in combination with a stellar evolutionary model that provides ...
Andre, Baraffe, Bonnell, Christopher F. McKee, Connelley, Covey, Dunham, Dunham, Enoch, Enoch, Evans, Fuchs, Greene, Hartmann, Heiderman, Hosokawa, Hosokawa, Kirk, Kratter, Masunaga, McKee, McKee, McKee, McLaughlin, Mellon, Miller, Muzerolle, Myers, Myers, Offner, Offner, Offner, Palla, Pech, Robitaille, Sandell, Stella S. R. Offner, Tan, Vorobyov, White, White, Whitney, Young, Zhu   +43 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source