Results 161 to 170 of about 671,921 (343)

Gamma-ray bursts as tracers of star-formation rate and metallicity evolution with THESEUS [PDF]

, 2018
S. D. Vergani
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

The ALMaQUEST Survey. XIII. Understanding Radial Trends in Star Formation Quenching via the Relative Roles of Gas Availability and Star Formation Efficiency

The Astrophysical Journal
Star formation quenching is one of the key processes that shape the evolution of galaxies. In this study, we investigate the changes in molecular gas and star formation properties as galaxies transit from the star-forming main sequence to the passive ...
Hsi-An Pan, Lihwai Lin, Sara L. Ellison, Mallory D. Thorp, Sebastián F. Sánchez, Asa F. L. Bluck, Francesco Belfiore, Joanna M. Piotrowska, Jillian M. Scudder, William M. Baker   +9 more
doaj   +1 more source

Spectral Analysis of Star-Forming Galaxies at z < 0.4 with FADO: Impact of Nebular Continuum on Galaxy Properties

Universe
The star formation rate (SFR) is a crucial astrophysical characteristic for understanding the formation and evolution of galaxies, determining the interplay between the interstellar medium and stellar activity. The mainstream approach to studying stellar
Yaosong Yu, Qihang Chen, Liang Jing, Ciro Pappalardo, Henrique Miranda   +4 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

The Evolution of Molecular Clouds: Turbulence-regulated Global Radial Collapse

The Astrophysical Journal
The star formation efficiency (SFE) measures the proportion of molecular gas converted into stars, while the star formation rate (SFR) indicates the rate at which gas is transformed into stars.
An-Xu Luo, Hong-Li Liu, Jin-Zeng Li
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Using [C ii] 158 μm Emission from Isolated ISM Phases as a Star Formation Rate Indicator [PDF]

, 2019
Jessica Sutter, Daniel A. Dale, Kevin V. Croxall, Eric W. Pelligrini, J. D. T. Smith, Philip N. Appleton, Pedro Beirão, Alberto D. Bolatto, Daniela Calzetti, Alison Crocker, Ilse De Looze, Bruce Draine, Maud Galametz, Brent A. Groves, George Helou, Rodrigo Herrera-Camus, Leslie K. Hunt, Robert C. Kennicutt, Hélène Roussel, Mark G. Wolfire   +19 more
openalex   +1 more source

Revisiting the Relationship between the Long GRB Rate and Cosmic Star Formation History Based on a Large Swift Sample [PDF]

, 2020
Jing-Meng Hao, Liang Cao, You-Jun Lu, Qing-Bo Chu, Jun-Hui Fan, Ye-Fei Yuan, Yu-Hai Yuan   +6 more
openalex   +1 more source