Results 301 to 310 of about 636,610 (341)

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Planets larger than Neptune have elevated eccentricities. [PDF]

open access: yesProc Natl Acad Sci U S A
Gilbert GJ, Petigura EA, Entrican PM.
europepmc   +1 more source

Retrograde intrarenal surgery with intelligent pressure control: experience from a primary hospital in China. [PDF]

open access: yesBMC Urol
Liu X   +10 more
europepmc   +1 more source

Earth-mass planets with He atmospheres in the habitable zone of Sun-like stars. [PDF]

open access: yesNat Astron
Lammer H   +6 more
europepmc   +1 more source

Genomic characterization and pre-clinical evaluation of a new polyvalent lytic Loughborough phage. [PDF]

open access: yesAppl Microbiol Biotechnol
Sherif MM   +3 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy