Results 211 to 220 of about 47,546 (266)
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
SAM68 is a multifunctional post-transcriptional regulator of cardiomyocyte differentiation. [PDF]
Broglia L +18 more
europepmc +1 more source
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Protocol for condensate-based stabilization of gene circuit dynamics under growth-mediated dilution in E. coli. [PDF]
Zhang R, Tian XJ.
europepmc +1 more source
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Kinetic Jeans instability in FOG framework. [PDF]
Das M, Atteya A, Karmakar PK.
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Essential Role of Icosahedral Symmetry in the 3D Shape of AuAg Plasmonic Nanostars With High Aspect-Ratio Legs. [PDF]
Corrêa LM +7 more
europepmc +1 more source
Floral Anatomy, Sporogenesis, and Gametogenesis in the Rubber Dandelion (<i>Taraxacum kok-saghyz</i>): Implications for Breeding and Crop Development. [PDF]
Schuchovski C +4 more
europepmc +1 more source

