Results 161 to 170 of about 59,534 (217)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Injectable living hydrogel as engineered biotherapeutic to promote tooth-extraction wound healing and alveolar bone regeneration. [PDF]

Bioact Mater
Guo J, Lei W, Li B, Li K, Li J, Wang Z, Liu H, Huang C, Shen Y.   +8 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Preserving enzyme conformation and catalytic efficiency in crowded and active environments. [PDF]

Nanoscale Adv
Maiti A, Nividha, Dey KK.
europepmc   +1 more source

Exploring long-term follow-up of effective implementation trials in schools: a secondary review. [PDF]

Front Public Health
Gardner C, Hall A, Lane C, Zucca A, McCrabb S, Riley-Gibson E, Loh XT, Farragher K, Sutherland R, Nathan N.   +9 more
europepmc   +1 more source

Immunogenicity and protection mediated by dmLT and alum adjuvants for an HIV-1 vaccine. [PDF]

Front Immunol
Stokdyk K, Sahoo A, Gangadhara S, Williams LD, Styles TM, Hellman CA, Zhang L, Odeh AJ, Flaherty S, Shen X, Rahman MA, Norton EB, Franchini G, Montefiori D, Kozlowski PA, Tomaras GD, Amara RR.   +16 more
europepmc   +1 more source

A cul-de-sac effect makes Emilia-Romagna more prone to floods in a changing climate. [PDF]

Sci Rep
Scoccimarro E, Borrelli A, Sangelantoni L, Cavicchia L, Pasqui M, Tibaldi S, Boccaletti G.   +6 more
europepmc   +1 more source

mRNA expression of NLRP3 and IL1B in inflammatory bowel diseases: a systematic review and meta-analysis. [PDF]

BMC Gastroenterol
Metselaar PI, Schilder RCH, Kraneveld AD, Te Velde AA, Li Yim AYF.   +4 more
europepmc   +1 more source

Sedentary behavior during pregnancy and risk of pre-eclampsia and/or gestational hypertension: A systematic review. [PDF]

Int J Gynaecol Obstet
Pei LX, Marozoff S.
europepmc   +1 more source