Results 151 to 160 of about 85,147 (265)

Best practices on blood and blood products for a prehospital hemorrhage protocol: consensus from the 2025 Canadian prehospital transfusion summit. [PDF]

Scand J Trauma Resusc Emerg Med
Peddle M, Greene A, Trojanowski J, Shih AW, Chang E, Nahirniak S, Pearson D, Prokopchuk-Gauk O, Martin D, Froh J, Musuka C, Seidl C, Lin Y, MacDonald S, Richards L, Farrell M, Miller D, Mack J, Da Luz L, Drennan IR, Singh K, Shingala D, Nolan B.   +22 more
europepmc   +1 more source

The Catalog of early-type Runaway stars from LAMOST-DR8

Runaway stars are OB-type stars ejected from their birthplace with large peculiar velocities. The leading hypothesis addressed in their formation includes the supernova ejection mechanism and the dynamic ejection scenario.
Liu, Chao, Han, ZhanWen, Chen, XueFei, Wang, Luqian, Wu, You, Guo, Yanjun   +5 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Urinary Cells Flow Cytometry in Renal Disease: A Systematic Review of Diagnostic and Prognostic Applications. [PDF]

Biomedicines
Prieto-Utrera RD, Priede-Vimbela JM, Vives M, Jorge-Monjas P, Bernardo D, Tamayo-Velasco Á, Poves-Álvarez R, Tamayo E, García-Concejo A.   +8 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Galactic Motions of The Early Type Stars

Galactic Motions of The Early Type Stars
The statistical analysis of the radial velocities of early type stars within 3 kpc from the sun is carried out on the assumption that the velocity field of the stars in the Galaxy is non-circuler and axially symmetric. The coincidence of the rotational velocities between the early type stars and neutral hydrogen is found. But the rotation curve derived
openaire  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Efficacy and tolerability of linezolid as an adjunctive treatment for nontuberculous mycobacterial infections in patients with adult-onset immunodeficiency syndrome: a prospective cohort study. [PDF]

Ann Med
Phoompoung P, Chavapradit N, Foongladda S, Chirapapaisan N, Suputtamongkol Y, Angkasekwinai N.   +5 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Comparative radioprotective effects of ascorbic acid and telmisartan, alone and in combination, on gamma-irradiated mandibular bone: an experimental rat study. [PDF]

Saudi Dent J
Abdel-Aziz LM, Esmail RM, Abdelfatah H, Sayed AI.   +3 more
europepmc   +1 more source