Results 211 to 220 of about 85,442 (265)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Co-STARS: a feasibility evaluation of a co-produced mental health literacy training package to reduce mental health inequities for Black young people in underserved communities - study protocol for a randomised controlled trial with an external pilot, process evaluation and economic analysis. [PDF]

open access: yesBMJ Open
Kumarendran B   +15 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Early Reprogramming Intermediates Enable Direct Neuronal Conversion Via NGN2. [PDF]

open access: yesJ Mol Neurosci
Angiolillo S   +6 more
europepmc   +1 more source

Early Feasibility and Efficacy of a Novel Skill-Based Training Program for Poststroke Dysphagia. [PDF]

open access: yesArch Rehabil Res Clin Transl
Bahia MM   +3 more
europepmc   +1 more source

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