Results 31 to 40 of about 9,157 (217)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Observations of southern emission-line stars
The Astrophysical Journal Supplement Series, 1976 A catalog of 1929 stars showing H-alpha emission on photographic plates is presented which covers the entire southern sky south of declination -25 deg to a red limiting magnitude of about 11.0. The catalog provides previous designations of known emission-line stars equatorial (1900) and galactic coordinates, visual and photographic magnitudes, H-alpha ...
openaire +1 more source
Symbiotic stars and other Hα emission-line stars towards the Galactic bulge★ [PDF]
Monthly Notices of the Royal Astronomical Society, 2013 Symbiotic stars are interacting binaries with the longest orbital periods and their multi-component structure makes them rich astrophysical laboratories. The accretion of a high mass loss rate red giant wind on to a white dwarf (WD) makes them promising Type Ia supernovae (SNe Ia) progenitors.
B. Miszalski +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
A Study of Emission Lines in Carbon Stars
The Astrophysical JournalAbstract Carbon stars are chemically peculiar stars with high carbon abundance, showing strong carbon molecule bands and rare emission lines in their spectra. This paper explores the stellar activity of carbon stars by identifying emission line features in their spectra.
Lichan Zhou +5 more
openaire +2 more sources
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Star Clusters in Quasars: Bloated Stars as Broad Emission Line Clouds [PDF]
Symposium - International Astronomical Union, 1989 Many scenarios of the evolution of star clusters in the centers of galaxies involve the formation of a central supermassive object. Since black hole formation is not 100% efficient in mass usage, stars are left over. This paper investigates the properties of such stars and proposes that their externally heated atmospheres become “bloated” due to ...
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Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
On the Interpretation of the Emission Lines in Stars of Early Spectral Class
The Astrophysical Journal, 1932 The emission-line spectra.-The presence of bright Fe II in the spectra of Be stars suggests that lines of other elements requiring similar conditions of excitation may also be present. A search in the spectra of several stars yielded definite evidence of the presence of Mg II and Si II; Sc II, Cr II, and Ni II are probably present; forbidden Fe II is ...
Struve, Otto, Swings, Polydore
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Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source