Results 31 to 40 of about 919 (215)
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A Catalog of Early-type Hα Emission-line Stars and 62 Newly Confirmed Herbig Ae/Be Stars from LAMOST Data Release 7 [PDF]
Yun-Jin Zhang +8 more
openalex +1 more source
On the Formation of Balmer Emission Lines in the Model Envelopes of Be Stars [PDF]
We consider the formation of the Balmer emission lines and the decrement Hα/Hβ/Hγ, by solving the non-LTE problems in elementary regions of the envelope divided by equal line-of-sight velocities. These envelope-elements are characterized by different optical depths in the Balmer lines and by different dilution factors for the incident stellar radiation.
T. Kogure, S. Suzuki, M. Mon
openaire +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Non-emission-line young stars of intermediate mass [PDF]
7 pages, 5 figures, accepted by ...
Manoj, P., Maheswar, G., Bhatt, H. C.
openaire +2 more sources
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Spectroscopy of unusual emission-line stars
New spectroscopic observations are reported for ten stars that have been identified in the literature as having H-alpha emission with suspected F, G, or K spectral types. Three of the stars are shown to be BE stars, two are confirmed as early-type supergiants, three show composite (F or K + B) spectra, one is a 'post-T Tauri' star, and one is an ...
openaire +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source

