Results 171 to 180 of about 27,773 (218)

No Evidence Supports the Presence of SRF-type MADS-Box Genes in Land Plants. [PDF]

Genome Biol Evol
Qiu Y, Li Z, Köhler C.
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Patterns and Clinical Efficacy of Biologics Switching in Patients With Severe Asthma: A Systematic Review and Meta-Analysis. [PDF]

Allergy
Zheng Y, Li YC, Li SJ, Xu M, Hu JQ, Tian WQ, Chen SW, Li XH, He Y, Lu G, Akdis M, Agache I, Akdis CA, Gao YD.   +13 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Adaptive Laboratory Evolution Unlocks Membrane Permeability as a Key Limitation in Long-Chain Alcohol Metabolism by Pseudomonas putida KT2440. [PDF]

Microb Biotechnol
Mireles R, Noda-García L.
europepmc   +1 more source

Hydroxyl-radical-specific cascade photogeneration for oxygen-chain photocatalytic therapy. [PDF]

Chem Sci
Liu Q, Yan C, Li X, Huang H, Fan Z, Zhang J, Zhang W, Shi P, Zhao Y, Guo Z, Zhu WH.   +10 more
europepmc   +1 more source

2D to 3D: Exploring Variation of Niche Dimensionality Across Consumers in a Coastal Arctic Ecosystem and Implications on Interpretation. [PDF]

Ecol Evol
Carvalho PC, Johnson KF, Elliott KH, Ferguson SH, Fisk AT, Gilchrist HG, Hedges KJ, Love OP, Mundy CJ, Niemi A, Ogloff WR, Rosenberg B, Watt CA, Yurkowski DJ.   +13 more
europepmc   +1 more source

Nonlinear Imaging Allows to Characterize Granulomas and Fibrosis in Mice Tissue From Experimental Schistosomiasis. [PDF]

J Biophotonics
da Fonseca GR, Lima RRM, Soares RE, Ribeiro BRM, Cabral Filho PE, Fontes A, de Paula AM.   +6 more
europepmc   +1 more source

Good vibrations: Exploring how orbital resonance shapes the Galilean moons. [PDF]

Nat Commun
Veenstra A, van Woerkom Q, Marzolini A, Fayolle S, Filice V.   +4 more
europepmc   +1 more source

Promoters of cooperation in evolutionary games. [PDF]

Proc Natl Acad Sci U S A
Svoboda J, Chatterjee K.
europepmc   +1 more source