Results 21 to 30 of about 921 (218)

Elevated Liver Enzymes Is Not an Impediment to Allopurinol Dose Escalation: An Observational Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Routine liver enzyme monitoring is advocated for while on allopurinol, but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzyme levels in patients with gout commenced on allopurinol. Methods One hundred and fifty patients with gout and normal baseline serum aminotransferases initiated on ...
May Shuen Tang   +4 more
wiley   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi   +10 more
wiley   +1 more source

On negative infrared flares of flare stars

open access: yesThe Astrophysical Journal, 1988
The basic formulation of the so-called fast electron hypothesis is presented. According to this hypothesis, the optical flares of UV Cet-type stars are caused by the inverse compton effect, i.e., nonthermal interactions of infrared photons with fast electrons (E equal to about 1.5 MeV), as well as nonthermal bremsstrahlung.
openaire   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

open access: yesAdvanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib   +8 more
wiley   +1 more source

New EUV Selected Flare Stars [PDF]

open access: yesInternational Astronomical Union Colloquium, 1995
The ROSAT Wide Field Camera all-sky EUV survey of 1990-91 identified over 200 active late-type stars (Pounds et al. 1993). Most of these were not known to be active prior to the survey and follow-up optical spectroscopy has been successful in selecting the most active dMe stars.
Bill Ball, Gordon Bromage
openaire   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia   +15 more
wiley   +1 more source

A Catalogue of Flare Stars in the Cygnus Region [PDF]

open access: yesSymposium - International Astronomical Union, 1990
A catalogue of known flare stars in the region of the emission nebulae NGC 7000 - IC 5068-70 and IC 1318 a,b,c in Cygnus is presented. The UBV magnitudes and spectral types, as far as available, for 96 flare stars and their 144 flares were collected. Patrol observations from the Asiago, Byurakan, Konkoly, Rozhen and Tonantzintla observatories, covering
Milcho K. Tsvetkov, Katya P. Tsvetkova
openaire   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

open access: yesAdvanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang   +9 more
wiley   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

open access: yes
Arthritis Care &Research, EarlyView.
Catherine Deffendall   +6 more
wiley   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

open access: yesAdvanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei   +17 more
wiley   +1 more source

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