Results 121 to 130 of about 38,720 (218)

The Association Between Platelet Indices and Osteoarthritis: A Systematic Review and Meta-analysis. [PDF]

Clin Med Insights Arthritis Musculoskelet Disord
Raveendran D, Nagel M, Perry L, Bucknill A, Liu Z.   +4 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

The abundance and radial distribution of faint and ultra-faint dwarfs in galaxy clusters. [PDF]

Mon Not R Astron Soc
Sadhu P, Sales LV, Navarro JF, Errani R, Benavides J, Peng EW.   +5 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Malignant Brenner tumor of the ovary: radiologic and histopathologic correlation demonstrating benign-to-malignant transition. [PDF]

Radiol Case Rep
Futaki N, Kamiishi T, Kato F, Mitamura T, Okada H, Kuwabara T, Tsuneta S, Yoshikawa M, Kimura R, Nishioka N, Sakamoto K, Sakurai M, Matsumiya H, Kurosu H, Yamazaki H, Ihira K, Endo D, Konno Y, Watari H, Kudo K.   +19 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Gravitational-wave constraints on the pair-instability mass gap and nuclear burning in massive stars. [PDF]

Nat Astron
Antonini F, Romero-Shaw IM, Callister T, Dosopoulou F, Chattopadhyay D, Ginat YB, Gieles M, Mapelli M.   +7 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Is Non-dominant Leg a Key Factor for Endurance Performance in Male Youth Soccer Players? Data-Driven Knowledge-Adjusted Causal Analysis and Literature Synthesis. [PDF]

Sports Med Open
Mikielewicz M, Korzeniewski K, Makuch R, Gąsior JS, Młyńczak M.   +4 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source