Results 31 to 40 of about 169 (167)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

The Spheroid Luminosity and Mass Functions From HST Star Counts

open access: yes, 1997
Clarifications and improvements made in response to referee ...
Gould, Andrew   +2 more
openaire   +2 more sources

Very Low Mass Stellar Populations in Star-Forming Regions: Near-Infrared Luminosity Functions and Mass Functions [PDF]

open access: yesSymposium - International Astronomical Union, 2003
We briefly describe recent studies of the low-mass young stellar populations including substellar objects and of their luminosity functions and mass functions, especially at lower-ends, in different star-forming regions. The mass function is determined by the technique based on the near-infrared photometry for estimating stellar luminosities and then ...
openaire   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

An infrared search for very low mass stars - The luminosity function

open access: yesThe Astrophysical Journal, 1983
Infrared photometry can reveal cool companions to hot sub-main-sequence stars to very faint limtis of luminosity. We have surveyed approx.100 white dwarfs at 2.2 ..mu..m for very low mass red dwarf companions in a search complete to M/sub v/approx.21. Very few new companions were found, none with M/sub v/>15.
openaire   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Bayesian inferences of galaxy formation from the K-band luminosity and H i mass functions of galaxies: constraining star formation and feedback [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2014
17 pages, 9 figures, 1 table, accepted for publication in ...
Lu, Yu   +4 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy