Results 171 to 180 of about 24,387 (198)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Psychological distress among bladder cancer patients: A systematic review. [PDF]

Urol Ann
Indraswari MT, Rahman F, Hamid ARAH, Mochtar CA.   +3 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Determination of the mass distribution of the first stars from the 21-cm signal. [PDF]

Nat Astron
Gessey-Jones T, Sartorio NS, Bevins HTJ, Fialkov A, Handley WJ, de Lera Acedo E, Mirouh GM, Izzard RG, Barkana R.   +8 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Radiotherapy and immunotherapy for advanced cancers: A meta-analysis of dose, sequencing, and survival patterns. [PDF]

Transl Oncol
Cao XJ, He XY, Yang Y, Zhu Q.
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Efficacy and heterogeneity: an exclusive human milk diet for necrotizing enterocolitis prevention in very preterm infants-a systematic review and meta-analysis of 11 studies. [PDF]

Front Nutr
Gao Y, Huang Z, Zou Y, Hu S, Chen W.
europepmc   +1 more source

Metformin enhances survival with immune checkpoint inhibitors in cancer patients: A meta-analysis. [PDF]

Oncol Lett
Qiao Y, Li H, Feng Y, Liang S, Hua D.
europepmc   +1 more source