Results 21 to 30 of about 11,734 (215)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

PRE-MAIN-SEQUENCE STARS IN THE CEPHEUS FLARE REGION [PDF]

The Astrophysical Journal Supplement Series, 2009
61 pages, 27 figures, 8 tables; accepted for publication by ...
Kun, M., Balog, Z., Kenyon, S. J., Mamajek, E. E., Gutermuth, R. A.   +4 more
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Pulsation in pre-main sequence stars [PDF]

Proceedings of the International Astronomical Union, 2015
AbstractAsteroseismology has been proven to be a successful tool to unravel details of the internal structure for different types of stars in various stages of evolution well after birth. We can now show that it has similar power for pre-main sequence (pre-MS) objects.
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Asteroseismology of pre-main sequence stars [PDF]

Communications in Asteroseismology, 2009
Intermediate-mass pre-main sequence (PMS) stars cross the instability region on their way to the main sequence and can become pulsationally unstable. The δ Scuti-like PMS pulsators populate the same area in the Hertzsprung-Russell (HR) diagram as the classical δ Scuti stars.
openaire   +1 more source

The pre-main-sequence star IP Persei [PDF]

Astronomy & Astrophysics, 2001
We present the results of high- and low-resolution spectroscopic and broadband multicolour photometric observations of the emission-line A-type star IP Per. Significant variations of the Balmer line profiles and near-IR brightness are detected.
A. S. Miroshnichenko, K. S. Bjorkman, E. L. Chentsov, V. G. Klochkova, R. O. Gray, P. García-Lario, J. V. Perea Calderón   +6 more
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source