Results 211 to 220 of about 1,652,070 (380)
Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam +14 morewiley +1 more sourceSTAR Collaboration
Nuclear Physics A, 2006 B.I. Abelev, J. Adams, M.M. Aggarwal, Z. Ahammed, J. Amonett, B.D. Anderson, M. Anderson, D. Arkhipkin, G.S. Averichev, Y. Bai, J. Balewski, O. Barannikova, L.S. Barnby, J. Baudot, S. Bekele, V.V. Belaga, A. Bellingeri-Laurikainen, R. Bellwied, F. Benedosso, S. Bhardwaj, A. Bhasin, A.K. Bhati, H. Bichsel, J. Bielcik, J. Bielcikova, L.C. Bland, S.-L. Blyth, B.E. Bonner, M. Botje, J. Bouchet, A.V. Brandin, A. Bravar, M. Bystersky, R.V. Cadman, X.Z. Cai, H. Caines, M. Calderón de la Barca Sánchez, J. Castillo, O. Catu, D. Cebra, Z. Chajecki, P. Chaloupka, S. Chattopadhyay, H.F. Chen, J.H. Chen, J. Cheng, M. Cherney, A. Chikanian, W. Christie, J.P. Coffin, T.M. Cormier, M.R. Cosentino, J.G. Cramer, H.J. Crawford, D. Das, S. Das, M. Daugherity, M.M. de Moura, T.G. Dedovich, M. DePhillips, A.A. Derevschikov, L. Didenko, T. Dietel, P. Djawotho, S.M. Dogra, W.J. Dong, X. Dong, J.E. Draper, F. Du, V.B. Dunin, J.C. Dunlop, M.R. Dutta Mazumdar, V. Eckardt, W.R. Edwards, L.G. Efimov, V. Emelianov, J. Engelage, G. Eppley, B. Erazmus, M. Estienne, P. Fachini, R. Fatemi, J. Fedorisin, K. Filimonov, P. Filip, E. Finch, V. Fine, Y. Fisyak, J. Fu, C.A. Gagliardi, L. Gaillard, M.S. Ganti, V. Ghazikhanian, P. Ghosh, J.E. Gonzalez, Y.G. Gorbunov, H. Gos, O. Grebenyuk, D. Grosnick, S.M. Guertin, K.S.F.F. Guimaraes, N. Gupta, T.D. Gutierrez, B. Haag, T.J. Hallman, A. Hamed, J.W. Harris, W. He, M. Heinz, T.W. Henry, S. Hepplemann, B. Hippolyte, A. Hirsch, E. Hjort, A.M. Hoffman, G.W. Hoffmann, M.J. Horner, H.Z. Huang, S.L. Huang, E.W. Hughes, T.J. Humanic, G. Igo, P. Jacobs, W.W. Jacobs, P. Jakl, F. Jia, H. Jiang, P.G. Jones, E.G. Judd, S. Kabana, K. Kang, J. Kapitan, M. Kaplan, D. Keane, A. Kechechyan, V.Yu. Khodyrev, B.C. Kim, J. Kiryluk, A. Kisiel, E.M. Kislov, S.R. Klein, A. Kocoloski, D.D. Koetke, T. Kollegger, M. Kopytine, L. Kotchenda, V. Kouchpil, K.L. Kowalik, M. Kramer, P. Kravtsov, V.I. Kravtsov, K. Krueger, C. Kuhn, A.I. Kulikov, A. Kumar, A.A. Kuznetsov, M.A.C. Lamont, J.M. Landgraf, S. Lange, S. LaPointe, F. Laue, J. Lauret, A. Lebedev, R. Lednicky, C.-H. Lee, S. Lehocka, M.J. LeVine, C. Li, Q. Li, Y. Li, G. Lin, X. Lin, S.J. Lindenbaum, M.A. Lisa, F. Liu, H. Liu, J. Liu, L. Liu, Z. Liu, T. Ljubicic, W.J. Llope, H. Long, R.S. Longacre, W.A. Love, Y. Lu, T. Ludlam, D. Lynn, G.L. Ma, J.G. Ma, Y.G. Ma, D. Magestro, D.P. Mahapatra, R. Majka, L.K. Mangotra, R. Manweiler, S. Margetis, C. Markert, L. Martin, H.S. Matis, Yu.A. Matulenko, B. Mohanty, M.G. Munhoz, T.K. Nayak, V. Okorokov, R. Picha, M. Planinic, N. Poljak, M. Potekhin, R. Sahoo, K. Schweda, J. Seger, A. Stadnik, M. Strikhanov, A.A.P. Suaide, M. Sumbera, M. van Leeuwen, I.-K. Yoo +216 moreopenaire +5 more sourcesTonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes +17 morewiley +1 more sourceAberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu +12 morewiley +1 more source
