Results 241 to 250 of about 562,063 (305)

Comparison of liver T1 estimates generated by breath-hold 3D FSPGR and free-breathing 3D radial stack-of-stars FSPGR variable flip angle T1 mapping sequences. [PDF]

Eur J Radiol Open
Xu H, Hou Z, Zhang M, Guo R, Zhang J, Fu G, Wen Q, Li Z, Tao F, Yang S.   +9 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

To the stars

, 2015
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Multimodality evaluation of bilateral parotid oncocytomas: A rare case report and literature review. [PDF]

Radiol Case Rep
Anwar S, Mubarak F, Mahmood A, Ahmed M.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Precision Enhancement of Multi-Source Integrated Navigation via Solar Disk Differential Velocity Compensation. [PDF]

Sensors (Basel)
Huang Y, Ning X.
europepmc   +1 more source

Using cognitive interviews with children to test the content validity of a paediatric patient reported experience measure. [PDF]

BMJ Paediatr Open
Barr KR, Fortunati E, Studniberg Z, Nikolovski J, White L, Elliott S, McCartney L, Smith-McCue D, Noah M, Swaminathan G, John JR, Treadgold C, Hall A, Dadich A, Vernon B, Toscano E, Hiscock H, Chow J, Johnston L, Whitehead L, Foster M, Sung V, Eapen V.   +22 more
europepmc   +1 more source