Results 51 to 60 of about 262,934 (297)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

CHOICE AND VALIDATION OF TEAMBUILDING MODEL OF SERVICE ORGANIZATIONS MANAGEMENT

open access: yesAdvanced Engineering Research, 2011
A complex of teambuilding principles for the service organizations management is offered. A model of tripartite exchange based on the innovative organizational environment is described.
Sergey V. Petrov
doaj  

Decomposition of Complete Multigraphs Into Stars and Cycles

open access: yesDiscussiones Mathematicae Graph Theory, 2015
Let k be a positive integer, Sk and Ck denote, respectively, a star and a cycle of k edges. λKn is the usual notation for the complete multigraph on n vertices and in which every edge is taken λ times.
Beggas Fairouz   +2 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Saturation Spectrum of Paths and Stars

open access: yesDiscussiones Mathematicae Graph Theory, 2017
A graph G is H-saturated if H is not a subgraph of G but the addition of any edge from G̅ to G results in a copy of H. The minimum size of an H-saturated graph on n vertices is denoted sat(n,H), while the maximum size is the well studied extremal number,
Faudree Jill   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Discovery of a Long Thermonuclear X-Ray Burst from the Ultracompact Binary 4U 1850–087

open access: yesThe Astrophysical Journal
We report the detection of a long X-ray burst from the ultracompact binary 4U 1850–087. The type I X-ray burst was observed on MJD 60171.65 by the Monitor of All-sky X-ray Image and Neutron Star Interior Composition Explorer (NICER). We analyze the NICER
Yongqi Lu   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

On soft factors and transmutation operators

open access: yesJournal of High Energy Physics
The well known soft theorems state the specific factorizations of tree level gravitational (GR) amplitudes at leading, sub-leading and sub-sub-leading orders, with universal soft factors.
Fang-Stars Wei, Kang Zhou
doaj   +1 more source

Home - About - Disclaimer - Privacy