Results 71 to 80 of about 100,543 (199)

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

STAR Collaboration

Nuclear Physics A, 2006
B.I. Abelev, J. Adams, M.M. Aggarwal, Z. Ahammed, J. Amonett, B.D. Anderson, M. Anderson, D. Arkhipkin, G.S. Averichev, Y. Bai, J. Balewski, O. Barannikova, L.S. Barnby, J. Baudot, S. Bekele, V.V. Belaga, A. Bellingeri-Laurikainen, R. Bellwied, F. Benedosso, S. Bhardwaj, A. Bhasin, A.K. Bhati, H. Bichsel, J. Bielcik, J. Bielcikova, L.C. Bland, S.-L. Blyth, B.E. Bonner, M. Botje, J. Bouchet, A.V. Brandin, A. Bravar, M. Bystersky, R.V. Cadman, X.Z. Cai, H. Caines, M. Calderón de la Barca Sánchez, J. Castillo, O. Catu, D. Cebra, Z. Chajecki, P. Chaloupka, S. Chattopadhyay, H.F. Chen, J.H. Chen, J. Cheng, M. Cherney, A. Chikanian, W. Christie, J.P. Coffin, T.M. Cormier, M.R. Cosentino, J.G. Cramer, H.J. Crawford, D. Das, S. Das, M. Daugherity, M.M. de Moura, T.G. Dedovich, M. DePhillips, A.A. Derevschikov, L. Didenko, T. Dietel, P. Djawotho, S.M. Dogra, W.J. Dong, X. Dong, J.E. Draper, F. Du, V.B. Dunin, J.C. Dunlop, M.R. Dutta Mazumdar, V. Eckardt, W.R. Edwards, L.G. Efimov, V. Emelianov, J. Engelage, G. Eppley, B. Erazmus, M. Estienne, P. Fachini, R. Fatemi, J. Fedorisin, K. Filimonov, P. Filip, E. Finch, V. Fine, Y. Fisyak, J. Fu, C.A. Gagliardi, L. Gaillard, M.S. Ganti, V. Ghazikhanian, P. Ghosh, J.E. Gonzalez, Y.G. Gorbunov, H. Gos, O. Grebenyuk, D. Grosnick, S.M. Guertin, K.S.F.F. Guimaraes, N. Gupta, T.D. Gutierrez, B. Haag, T.J. Hallman, A. Hamed, J.W. Harris, W. He, M. Heinz, T.W. Henry, S. Hepplemann, B. Hippolyte, A. Hirsch, E. Hjort, A.M. Hoffman, G.W. Hoffmann, M.J. Horner, H.Z. Huang, S.L. Huang, E.W. Hughes, T.J. Humanic, G. Igo, P. Jacobs, W.W. Jacobs, P. Jakl, F. Jia, H. Jiang, P.G. Jones, E.G. Judd, S. Kabana, K. Kang, J. Kapitan, M. Kaplan, D. Keane, A. Kechechyan, V.Yu. Khodyrev, B.C. Kim, J. Kiryluk, A. Kisiel, E.M. Kislov, S.R. Klein, A. Kocoloski, D.D. Koetke, T. Kollegger, M. Kopytine, L. Kotchenda, V. Kouchpil, K.L. Kowalik, M. Kramer, P. Kravtsov, V.I. Kravtsov, K. Krueger, C. Kuhn, A.I. Kulikov, A. Kumar, A.A. Kuznetsov, M.A.C. Lamont, J.M. Landgraf, S. Lange, S. LaPointe, F. Laue, J. Lauret, A. Lebedev, R. Lednicky, C.-H. Lee, S. Lehocka, M.J. LeVine, C. Li, Q. Li, Y. Li, G. Lin, X. Lin, S.J. Lindenbaum, M.A. Lisa, F. Liu, H. Liu, J. Liu, L. Liu, Z. Liu, T. Ljubicic, W.J. Llope, H. Long, R.S. Longacre, W.A. Love, Y. Lu, T. Ludlam, D. Lynn, G.L. Ma, J.G. Ma, Y.G. Ma, D. Magestro, D.P. Mahapatra, R. Majka, L.K. Mangotra, R. Manweiler, S. Margetis, C. Markert, L. Martin, H.S. Matis, Yu.A. Matulenko, B. Mohanty, T.K. Nayak, V. Okorokov, R. Picha, M. Planinic, N. Poljak, M. Potekhin, R. Sahoo, K. Schweda, J. Seger, A. Stadnik, M. Strikhanov, A.A.P. Suaide, M. Sumbera, M. van Leeuwen, I.-K. Yoo   +215 more
openaire   +5 more sources

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

The photometry and kinematics studies of NGC 2509 derived from Gaia DR3. [PDF]

Sci Rep
Ahmed NM, Tadross AL.
europepmc   +1 more source

Starred [PDF]

Journal of Thrombosis and Haemostasis, 2015
F R, Rosendaal, P H, Reitsma
openaire   +2 more sources