Results 201 to 210 of about 10,149,169 (290)

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Can Neurotech Help Tame Brain Tumors? [PDF]

J Med Internet Res
Spichak S.
europepmc   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Identifying Pregnancies in Population-Based Data Sources: Development and Application of the ConcePTION Pregnancy Algorithm. [PDF]

Pharmacoepidemiol Drug Saf
Limoncella G, Girardi A, Bartolini C, Hyeraci G, Roberto G, Paoletti O, Messina D, Villalobos F, Bisacco CA, van den Berg J, Houben E, Santacà K, Ingrasciotta Y, Trifirò G, Pellegrini G, Ientile V, Hoxhaj V, Durán C, Riera-Arnau J, García-Poza P, Martín-Pérez M, Llorente-García A, Cea-Soriano L, Huerta-Álvarez C, Sánchez-Sáez F, Sanfélix-Gimeno G, Rodríguez-Bernal CL, Jové J, Bernard MA, Thurin NH, Jordan S, Thayer D, Evans HT, Coldea AI, Manfrini M, van Gelder M, Tari M, Pajouheshnia R, Afonso Maciel AS, Le Noan-Lainé M, Mølgaard-Nielsen D, Cunnington M, Dodd C, Grilli L, Andaur Navarro CL, Sturkenboom M, Nordeng H, Gini R.   +47 more
europepmc   +1 more source

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

Antibiotic development and a path to access in India. [PDF]

Nat Commun
Manesh A, Walia K, Saiyed T, Veeraraghavan B, Paterson DL.   +4 more
europepmc   +1 more source

From Flow to Function: Using Different Static Mixers to Fabricate Microarchitected Materials Via Chaotic Printing

Advanced Science, EarlyView.
Complex microarchitectures emerge from simple flow‐driven transformations as static mixers iteratively reorient and split material domains. Coupled with diverse deposition strategies, chaotic printing provides an accessible platform for fabricating architected materials that support biologically and chemically relevant processes. ABSTRACT Nature builds
Edna Johana Bolívar‐Monsalve, Carlos Fernando Ceballos‐González, Diego Alonso Quevedo‐Moreno, Irving Isaí Rendón‐Moreno, Ariel Cantoral‐Sánchez, Héctor Ambriz‐González, Mario Moisés Alvarez, Grissel Trujillo‐de Santiago   +7 more
wiley   +1 more source

Changes in perceived psychosocial working conditions after psychotherapeutic consultation at work - exploratory post-hoc analyses from a randomized controlled trial. [PDF]

BMC Public Health
Weber J, Hander NR, Angerer P, Mulfinger N, Schröder UB, Hansmann M, Herold R, Kröger C, Gündel H, Rothermund-Nassir E, Heming M.   +10 more
europepmc   +1 more source

A Universal Protein Ladder for Standardization of Diverse FRET Assays

Advanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith, Katie L. Gelder, Lewis Hunter‐Craig, Daniel A. Bose, Timothy D. Craggs, Alison E. Twelvetrees   +5 more
wiley   +1 more source

Light people: Radha Nagarajan, Marvell CTO and NAE member. [PDF]

Light Sci Appl
Wan Y, Guo C.
europepmc   +1 more source