Results 121 to 130 of about 16,735,230 (295)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Impact of Start-Up Incubator Service On the Start-up Performance
null 황보윤, null 김재형
openaire +1 more source
The Social Capital of Venture Capitalists and Its Impact on the Funding of Start-Up Firms [PDF]
How does the social capital of venture capitalists (VCs) affect the funding of start-ups? Extant entrepreneurship literature conceptualizes a substitute effect between the social and financial capital that new firms attain from their investors.
Sandner, P.G. +3 more
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
A MONITORING AND EVALUATION METHOD ON THE START-UP PERFORMANCE OF EMERGENCY DIESEL ENGINE
Emergency diesel engine is the last safety barrier for nuclear power plants. Nuclear safety criteria require that it can start up to rated speed( such as 1 500 r/min) within 10 seconds in an emergency and have loading conditions,so its startup ...
WANG Guan +3 more
doaj
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Editorial: Negotiating Gamer Identities
The term ‘gamer identity’ is hotly contested, and certainly not understood as a broadly accepted term. From the outdated stereotype of white, heterosexual, teenage boys playing Nintendo in their parents’ basement to the equally contested proclamation ...
de Wildt, Lars +8 more
core +2 more sources
On the Role of Entrepreneurial Experience for Start-up Financing: An Empirical Investigation for Germany [PDF]
Entrepreneurs are often faced with problems regarding start-up financing. But compared to novice entrepreneurs, experienced entrepreneurs should have both more knowledge and better contacts, which should potentially reduce the occurrence of problems and ...
Metzger, Georg
core +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Experimental Study on the Thermal Start-Up Performance of the Graphene/Water Nanofluid-Enhanced Solar Gravity Heat Pipe. [PDF]
Zhao S, Xu G, Wang N, Zhang X.
europepmc +1 more source

