Start-up performance - Open Access .click

Results 151 to 160 of about 16,735,230 (295)

The effects of culture as a start-up factor on business performance [PDF]

Problems and Perspectives in Management, 2014
Simon Radipere
doaj

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source

Discussion on Improvement of Start Performance of Asynchronous Motor and Calculation of Its Parameter

Gong-kuang zidonghua, 2011
The paper analyzed the theory of improving start performance of coiling asynchronous motor and proposed a control scheme of improving start performance of asynchronous motor, namely parallelling chopper and start resistor of rotor rectifier circuit, and ...
HUI Wei-mi
doaj

Impact of Youth Start-Up Business Incubating System On the Start-Up Business Performance

Asia-Pacific Journal of Business Venturing and Entrepreneurship, 2013
null 황보윤, null 김재형, null 방중혁 +2 more
openaire +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

Start-up e nuove tecnologie, una reale opportunità di lavoro

, 2019
La relazione ha affrontato la disciplina dei rapporti di lavoro alle dipendenze delle start-up, con specifico riferimento alla deroga alla disciplina generale del contratto di lavoro a tempo determinato, agli spazi per la contrattazione collettiva nella ...
quadri giulio
core

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source

Influence of Small Retailers’ Start-Up Preparations on Business Performance: Start-Up Motivation

Journal of Distribution and Management Research, 2020
openaire +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source

Deployment Readiness of Anammox for Wastewater Treatment with Potential Carbon-Saving Benefits: Environmental Risks, Monitoring Requirements and Implementation Pathways. [PDF]

Microorganisms
Zhou Y +8 more
europepmc +1 more source

start-up
start-up companies
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environmental sciences
heat transfer performance