Results 111 to 120 of about 3,281,012 (248)
Starting School with Food Allergy: Listening to Parents' and Children's Voices!
, 2014 Starting school is an important event in the lives of young children and their families. It can be complicated by an allergy towards food, depending on the severity of the allergy and the issues that surround the child’s safety outside the home.
Said, Maria +3 more
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Journal of Higher Education, Athletics, Labor & InnovationThis qualitative phenomenological study examined the college transition experience of Black female student-athletes at a private, Mid-Atlantic, predominantly White, National Collegiate Athletic Association Division I institution.
Noël E. Dolan
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Experimental Study on Mechanism of the Masticatory Tooth Fracture : Method to Detect Starting Point of Fracture [PDF]
, 2006 P(論文)To investigate the mechanism of fracture of teeth, the starting point of the fractured site was specified and the structural appearance was observed by staining the tooth surface and cyclic-stress loading test.
イワミ, カツアキ +5 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The Method of Starting Air System Rough Calculation
The paper deals with diesel compressed air starting system calculation method based on the comparison between the compressed air efficient work and the work consumed by the air compression in the engine cylinder during the compression stroke. Approximate
Indriksons, Rihards +2 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2016 Abstrak Mekanisme soft starting merupakan salah satu solusi untuk mengatasi lonjakan arus besar yang terjadi saat motor listrik mulai bergerak. Salah satu permasalahan yang disebabkan lonjakan arus yang berlebihan adalah terbakarnya komponen rangkaian ...
Iyas Munawar, Fakih Irsyadi
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source